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NAPLEX > ID infections > Flashcards

ID infections Flashcards

1
Q

bugs to worry about in surgery

A

skin flora: staph, strep (gram negative only in select surgeries)

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2
Q

recommended start time for pre-op surgery

A

60 min before incision

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3
Q

preferred antibiotic for pre-op

A

cefazolin (clindamycin or vancomycin if allergy)

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4
Q

gram negative coverage in pre-op surgery

A

metronidazole, cefotetan, cefoxitin

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5
Q

common bugs in meningitis

A

neisseria meningitidis, strep pneumo, h influenzae

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6
Q

when to consider listeria monocytogenes in meningitis

A

neonates, >50y, immunocompromised

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7
Q

what is given with the first dose of antibiotic for tx of meningitis

A

dexamethasone to prevent neurological complications

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8
Q

neonate tx meningitis

A

ampicillin + (cefotaxime OR gentamicin)

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9
Q

1 month old to 50yo tx meningitis

A

(ceftriaxone or cefotaxime) + vancomycin

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10
Q

why is ceftriaxone NOT given to neonates

A

hyperbilirubinemia which can cause brain damage

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11
Q

meningitis patients who should receive vancomycin

A

> 1 month

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12
Q

bacteria in AOM

A

strep pneumo, h influenzae, moraxella

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13
Q

first line AOM antibiotics

A

amoxicillin, agumentin

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14
Q

clavulanate se

A

diarrhea

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15
Q

amoxicillin frequency

A

bid

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16
Q

pharyngitis antibiotics

A

penicillin, amoxicillin

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17
Q

sinusitus antibiotic

A

augmentin

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18
Q

pertussis antibiotic treatment

A

macrolides

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19
Q

COPD exacerbation symptoms

A

inc dyspnea, inc sputum volume, inc sputum purulence

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20
Q

criteria to give antibiotics for acute COPD exacerbation

A

cardinal symptoms, mechanical ventilation

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21
Q

why is ciprofloxacin not given for CAP?

A

no strep pneumo coverage

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22
Q

CAP treatment with no comorbidities

A

beta lactam (amoxicillin)

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23
Q

CAP treatment with comorbidities

A

beta lactam + macrolide or daptomycin (need atypical coverage) OR FQ alone

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24
Q

CAP MRSA drugs

A

vancomycin, linezolid

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25
Q

CAP Psuedomonas drugs

A

zosyn, cefepime, meropenem

26
Q

False positive PPD test can occur with receipt of which vaccine

A

BCG

27
Q

drugs used in latent TB treatment

A

INH, rifampin, rifapentine

28
Q

active TB treatment

A

intensive 2 months: RIPE, continuation 4 months: rifampin and isoniazid

29
Q

rifampin major side effects

A

inc LFTs, hemolytic anemia, orange/red secretions

30
Q

major concern for rifampin

A

many DDIs!! (protease inhibitors, anticoags)

31
Q

isoniazid BBW

A

severe hepatitis (CI in active liver disease)

32
Q

pyrazinamide contraindications

A

acute gout, severe hepatic damage

33
Q

ethambutol contraindications

A

optic neuritis, inc LFTs

34
Q

Rifampin should NOT be used with

A

Anticoags: apixaban, rivaroxaban, edoxaban, dabigatran

35
Q

which RIPE drugs need interval adjustment with decreased renal function

A

pyrazinamide (CrCl<30), ethambutol (CrCl < 50)

36
Q

why should patients on isoniazid also take b6?

A

dec risk of peripheral neuropathy

37
Q

most common bugs in infective endocarditis

A

staph, streo, enterococci

38
Q

which antibiotic can be used to penetrate organisms in a biofilm

A

rifampin

39
Q

what is the rpeferred class used to treat infective endocarditis?

A

beta lactams or vancomycin

40
Q

dental prophylaxis regimen for patients at high risk of IE

A

amoxicillin 2 g

41
Q

spontaneous bacterial peritonitis should be empirically treated with

A

ceftriaxone

42
Q

intra-abdominal infection treatments that cover PEK, anaerobes, streptococci

A

ertapenem, moxifloxacin, cefuroxime/cefotaxime/ceftriaxone + metronidazole, cipro/levofloaxacin + metronidazole

43
Q

intra-abdominal infection tx that covers PEK, pseudomonas, enterobacter, anaerobes, strep, enterococci

A

Carbapenem (but NOT ertapenem), zosyn, cefepime/ceftazidime + metrnidazole

44
Q

common bacteria in SSTIs

A

strep, staph

45
Q

impetigo tx

A

local: mupirocin, numerous and extensive: cephalexin or dicloxacillin QID

46
Q

MRSA commonly causes which skin infections

A

folliculitis/furnuncle/carbuncle, abscess

47
Q

necrotizing fascitis empiric therapy

A

MRSA (vanc or dapto) + beta lactam (meropenem or zosyn) + clindamycin

48
Q

drug of choice for acute uncomplicated uti in pregnant women

A

amoxicillin, cephalexin

49
Q

acute pyelonephritis tx

A

quinolones, ceftriaxone

50
Q

urinary analgesic

A

phenazopyridine

51
Q

duration phenazopyridine

A

2 days

52
Q

c diff risk factors

A

antibiotics, healthcare exposure, PPI, advanced age, immunocompromised, obesity, previous CDI

53
Q

syphilis drug of choice

A

pen G

54
Q

gonorrhea drug of choice

A

ceftriaxone

55
Q

chlamydia drug of choice

A

doxycycline (azithromycin if pregnant)

56
Q

bacterial vaginosis drug of choice

A

metronidazole

57
Q

trichomoniasis drug of choice

A

metronidazole

58
Q

genital warts drug of choice

A

imiquimod

59
Q

imiquimod counseling

A

can weaken condoms and diaphragms–abstain from sex

60
Q

tickborne illness tx

A

doxycycline

NAPLEX (11 decks)

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