Immunizations Flashcards

1
Q

Provides recommendations for vaccine administration

A

ACIP (advisory committee on immunization practices)

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2
Q

CDC publishes ACIP recommendations in…

A

MMWR, pink book

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3
Q

Thimerosal can be found in…

A

multidose flu vaccines

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4
Q

geltain is used in vaccines as a…

A

stabilizer

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5
Q

another word for antibody

A

immunoglobulin

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6
Q

immunity gained from infection or vaccine is an example of…

A

active immunity

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7
Q

which type of vaccine produces a strong immune response (does not require booster)

A

live attenuated

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8
Q

contraindication for live vaccines

A

immunocompromised, pregnant

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9
Q

type of vaccine that may require a booster

A

inactivated

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10
Q

What are the common live vaccines?

A

TB, dengue, smallpox, ebola, MICRO-VY (MMR, Intranasal influenza, cholera, rotavirus, oral typhoid, varicella, yellow fever)

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11
Q

example of polysaccharide vaccine

A

pneumovax 23

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12
Q

example of conjugate vaccine

A

prevnar 20, menactra

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13
Q

example of recombinant vaccine

A

gardasil, flubok quadrivalent

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14
Q

how does a polysaccharide vaccine work?

A

uses sugar molecule from outside layer of bacteria

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15
Q

how does a conjugate vaccine work?

A

joins sugar molecules to proteins to inc immune response

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16
Q

how does a recombinant vaccine work?

A

gene of organism is inserted into gene of another cell and gets replicated

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17
Q

how does a toxoid vaccine work?

A

targets toxin produced by disease

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18
Q

how does an mRNA vaccine work?

A

gives instruction to cell to produce proteins specific to pathogen

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19
Q

Gardrasil 9

A

Human papillomavirus vaccine

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20
Q

Flublok quadrivalent

A

Recombinant influenza vaccine

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21
Q

Prevnar 20

A

Pneumococcal conjugate vaccine

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22
Q

Menactra

A

Meningitis conjugate

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23
Q

Pneumovax 23

A

Pneumococcal polysaccharide

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24
Q

A live vaccine can be given: a) simultaneously with inactivated vaccines b) 2 weeks after a different live vaccine c) four weeks after a different live vaccine

A

a,c

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25
Q

T/F: vaccines should be spaced out to allow time for immunity to build between vaccinations

A

F; should be given in least amount of trips to improve compliance

26
Q

What is the affect of increasing the interval between doses of a vaccine series?

A

delay complete protection, but does not diminish effectiveness

27
Q

antibody-containing products must be separated from…

A

MMR, varicella (2 weeks if vaccine first, 3 months if antibody first)

28
Q

Most live vaccines are withheld until the child reaches what age and why?

A

12 months; mother’s antibodies should be depleted by then so they will have a better response to the vaccine

29
Q

Which live vaccine may be given to infants?

A

rotavirus

30
Q

What vaccine series starts at birth?

A

hepatitis B

31
Q

Live vaccines may cause false-negatives on which test?

A

tuberculin skin test (PPD or tuberculosis test)

32
Q

Inactivated vaccines (can/cannot) cause disease

A

cannot

33
Q

HepB and HPV vaccines are contraindicated in

A

hypersensitivity to yeast

34
Q

Contraindications for live attenuated flu vaccines

A

severe egg allergy, aspirin-containing products, recent influenza antivirals, 2-4yo with asthma or wheezing, close contact with immunosuppressed

35
Q

varicella vaccine contraindication

A

gelatin or neomycin allergy

36
Q

rotavirus contraindication

A

history of intussusception

37
Q

yellow fever vaccine contraindication

A

egg allergy

38
Q

which flu vaccine is live?

A

intranasal

39
Q

Td or Tdap is given every

A

10 years

40
Q

shingrix is given when

A

at 50 yo or 19 yo and immunocompromised

41
Q

diabetics must have which vaccines

A

HepB, Pneumococcal

42
Q

vaccines given SC only

A

yellow fever, dengue, smallpox, monkeypox

43
Q

vaccines given only IM or SC

A

MMR, MMRV, varicella, PPSV23

44
Q

vaccines given intranasal only

A

flumist

45
Q

vaccines given only PO

A

typhoid, cholera, rotavirus

46
Q

T/F: it is recommended to give the patient APAP before vaccine administration

A

F

47
Q

which vaccines are stored in the freezer

A

varicella, MMRV, cholera oral

48
Q

which patient should receive the DTap vaccine? a) 5 year old child with no issues, b) adult with last booster 5 years ago

A

a; capital “D” is for children <7yo bc contains higher diphtheria component

49
Q

when is Td or Tdap indicated?

A

booster every 10y in adults (age 11-12 for teens), dirty wound prophylaxis, 3rd trimester of pregnancy, contact with infants or patients, 1 dose for children 7-10 yo with incomplete series

50
Q

how many doses fro DTaP?

A

five

51
Q

DTaP may be in a multi product formulation with…

A

Hib, HepB, IPV

52
Q

indication for Hib-containing vaccine

A

asplenia

53
Q

HPV vaccine contraindication

A

yeast allergy

54
Q

what is the most common vaccine preventable illness in the US?

A

the flu

55
Q

what patient population requires two doses of the flu vaccine?

A

6 mo. to 8 yrs (given 4 weeks apart)

56
Q

fluzone high dose and fluad are indicated for

A

65 years or older

57
Q

which flu vaccines are egg-free?

A

Flucelvax, Flublok

58
Q

MMR vaccine can be be given with which other live vaccine?

A

varicella

59
Q

how often should people at risk of menningicoccal disease be revaccinated?

A

every 5 years

60
Q

what age group can receive Bexsero?

A

10-25 years (MenB)

61
Q

where to store oral dose of typhoid vaccine

A

refrigerator (capsules)