IE

Question 1

Viridans Group Streptococci Endocarditis

Answer 1

Penicillin +/- Gentamicin
Ceftriaxone +/- Gentamicin

Vancomycin mono therapy

Question 2

Staphylococci (MSSA) Endocarditis

Answer 2

Nafcillin + Gentamicin
Cefazolin + Gentamicin
(+ Rifampin if prosthetic valve)

Vancomycin + Gentamicin

Question 3

Staphylococci (MRSA) Endocarditis

Answer 3

Vancomycin + Gentamicin

+Rifampin if prosthetic valve

Question 4

Enterococci Endocarditis

Answer 4

Penicillin + Gentamicin
Ampicillin + Gentamicin
(+ Rifampin if prosthetic valve)

Vancomycin + Gentamicin
Daptomycin
Linezolid

Question 5

Endocarditis Prophylaxis

Answer 5

Amoxicillin 2 grams 30-60 mins before procedure

Question 6

Endocarditis Prophylaxis NPO

Answer 6

Ampicillin 2 grams IM/IV

Cefazolin 1 grams IM/IV

Question 7

Endocarditis Prophylaxis Penicillin Allergy

Answer 7

Cephalexin 2 grams 
Cefadroxil 2 grams
Clindamycin 600mg 
Azithromycin 500mg
Clarithromycin 500mg

Question 8

Endocarditis Prophylaxis Penicillin Allergy NPO

Answer 8

Cefazolin 1 gram IM/IV
Ceftriaxone 1 gram IM/IV
Clindamycin 600mg IM/IV

Question 9

Healthy Community Acquired Pneumonia (CAP)

Answer 9

Azithromycin
Clarithromycin
Erythromycin

Doxycycline

Question 10

Drug resistant Community Acquired Pneumonia (CAP)

Answer 10

Beta-lactam + Macrolide
Beta-lactam + Doxycycline
(Amoxicillin, Amox/Clav, Cefpodoxime, Cefdinir, Cefuroxime, Ceftriaxone)

Moxifloxacin
Gemifloxacin
Levofloxacin

Question 11

Sinitus

Answer 11

Amoxicillin/Clav

2nd or 3rd gen cephalosporin +
Clindamycin, doxycycline, or respiratory quinolone

Question 12

Pharyngitis

Answer 12

Penicillin
Amoxicillin
1st/2nd gen cephalosporin

Macrolide

Question 13

Meningitis < 1 Month

Answer 13

Ampicillin + Cefotaxime

Ampicillin + Gentamicin

Question 14

Meningitis 1 - 23 Months

Answer 14

Ceftriaxone + Vancomycin

Cefotaxime + Vancomycin

Question 15

Meningitis 2 - 50 years

Answer 15

Ceftriaxone + Vancomycin

Cefotaxime + Vancomycin

Question 16

Meningitis > 50 years

Answer 16

Ceftriaxone + Vancomycin + Ampicillin

Cefotaxime + Vancomycin + Ampicillin

Question 17

Meningitis Penicillin Allergy

Answer 17

Moxifloxacin + Vancomycin +/- Bactrim

Levofloxacin + Vancomycin +/- Bactrim

Question 18

Acute Otitis Media

Answer 18

Amoxillin 80-90mg/kg/day

Amoc/Clav 90mg/kg/day

Question 19

Acute Otitis Media Penicillin Allergy

Answer 19

Cefdinir 14mg/kg/day
Cefuroxime 30mg/kg/day
Cefpodoxime 10mg/kg/day
Ceftriaxone 50mg/kg/day IM/IV

Question 20

Spontaneous Bacterial Peritonitis (SBP)

Answer 20

Ceftriaxone 5-7 days

Ampicillin
Gentamicin
Quinolone

Question 21

Spontaneous Bacterial Peritonitis (SBP) Prophylaxis

Answer 21

Bactrim
Ofloxacin
Ciprofloxacin

Question 22

Impetigo (Honey colored crusts)

Answer 22

Cephalexin 250 mg QID

Question 23

Folliculitis/Furuncles/Carbuncles

Answer 23

Cephalexin 500mg QID

Bactrim 1-2 Tabs BID
Doxycycline 100mg PO BID

Question 24

Cellulitis (Non-purulent) (Mild)

Answer 24

Cephalexin 500mg PO QID

Clindamycin 300mg PO QID
Pen VK, Dicloxacillin

Question 25

Abcsess (Purulent) (Mild to Moderate)

Answer 25

``` Bactrim Doxycycline Minocycline Clindamycin Linezolid ```

Question 26

Severe Purulent SSTI

Answer 26

Antibiotics with MRSA activity

Question 27

Necrotizing fasciitis

Answer 27

Vancomycin + (Piperacillin/tazobactam, imipenem/cilastatin, or meropenem)

Question 28

Acute uncomplicated cystitis

Answer 28

Nitrofurantoin 100mg PO BID with food x 5 days Bactrim BID x 3 days (>20% E. coli resistance rate) Fosfomycin 3 grams x 1 dose Amoxicillin/Clav Cephalosporin Ciprofloxacin Levofloxacin

Question 29

Acute uncomplicated pyelonephritis

Answer 29

Ciprofloxacin 500mg BID x 7 days Levofloxacin 750mg x 5 days (Only if Quinolone resistance <10%) Ceftriaxone 1 gram x 1 then quinolone (5-7 days) Aminoglycoside x 1 then quinolone (5-7 days) Bactrim x 14 days (Amox/clav, cefdinir, cefaclor, or cefpodoxime) x 10-14 days

Question 30

Acute uncomplicated cystitis pregnant

Answer 30

Cephalexin Amoxicillin Fosfomycin (if beta lactam allergy) 3-7 days

Question 31

Bacteriuria in pregnancy

Answer 31

Amox/clav Cephalosporin Nitrofurantoin Bactrim (should be avoided in 1st trimester)

Question 32

Travelers diarrhea

Answer 32

Azithromycin (if dysentery) (preffered in child and pregnant) Quinolones Rifaxamin

Question 33

Syphillis

Answer 33

Penicillin G benzathine (Bicillin L-A, NOT Bicillin) 2.4 million units IM x 1 Doxycycline 100mg BID Tetracycline 500mg QID x 14 days

Question 34

Late latent or tertiary Syphillis

Answer 34

Pen G Benzathine 2.4 million units IM weekly x 3 weeks Doxycycline x 28 days Tetracycline x 28 days

Question 35

Neurosyphillis and Congenital Syphillis

Answer 35

Penicillin G aqueous crystalline Penicillin G Procaine

Question 36

Gonorrhea

Answer 36

Ceftriaxone 250mg x IM x 1 + Azithromycin 1 gram x 1 | Ceftriaxone 250mg x IM x 1 + Doxycycline 100mg BID x 7 days

Question 37

Chlamydia

Answer 37

Azithromycin 1 gram x 1 | Doxycycline 100mg BID x 7 days

Question 38

Bacterial Vaginosis

Answer 38

Metronidazole Clindamycin Tinidazole Secnidazole

Question 39

Trichomoniasis

Answer 39

Metronidazole | recommended in all trimesters despite risk

Question 40

Genital Warts

Answer 40

Imiquimod