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PHRM 841 > IHD/HF Formulary Quiz > Flashcards

IHD/HF Formulary Quiz Flashcards

1
Q

Brand Name: Aspirin

A

Ecotrin (EC), Bayer Aspirin, Vazalore (liquid capsule)

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2
Q

Dosing: Aspirin

A

Loading Dose: 162-325 mg

Maintenance Dose: 81 mg

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3
Q

Adverse Effects: Aspirin

A

GI Bleeding

Intracranial/Extracranial Bleeding

Hypersensitivity

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4
Q

Brand Name: Atorvastatin

A

Lipitor

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5
Q

Dosing: Atorvastatin

A

40-80 mg (high intensity)

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6
Q

Adverse Effects: Atorvastatin

A

diarrhea

arthralgia

nasopharyngitis

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7
Q

Monitoring Parameter: Atorvastatin

A

lipid panel

hepatic transaminase levels

signs/symptoms of myopathy/rhabdomyolysis

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8
Q

Brand Name: Rosuvastatin

A

Crestor

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9
Q

Dosing: Rosuvastatin

A

20-40 mg (high intensity)

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10
Q

Adverse Effects: Rosuvastatin

A

myalgia

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11
Q

Monitoring Parameters: Rosuvastatin

A

lipid panel

hepatic transaminase levels

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12
Q

Brand Name: Clopidogrel

A

Plavix

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13
Q

Dosing: Clopidogrel

A

Loading Dose: 300 or 600 mg

Maintenance: 75 mg

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14
Q

Adverse Effects: Clopidogrel

A

bleeding (1% increase in major bleeding when added to ASA)

rash

diarrhea

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15
Q

Monitoring Parameters: Clopidogrel

A

signs of bleeding

hemoglobin and hematocrit periodically

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16
Q

Brand Name: Prasugrel

A

Effient

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17
Q

Dosing: Prasugrel

A

Loading Dose: 60 mg

Maintenance Dose: 10 mg daily

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18
Q

Adverse Effects: Prasugrel

A

bleeding (0.6% increase in major bleeding and 0.5% increase in life-threatening bleeding)

diarrhea

rash

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19
Q

Brand Name: Ticagrelor

A

Brilinta

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20
Q

Dosing: Ticagrelor

A

Loading Dose: 180 mg

Maintenance Dose: 90 mg BID

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21
Q

Adverse Effects: Ticagrelor

A

bleeding

bradycardia

heart block

dyspnea

1% risk of major bleeding

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22
Q

Monitoring Parameters: Ticagrelor

A

signs and symptoms of adverse effects

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23
Q

Brand Name: Pravastatin

A

Pravachol

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24
Q

Dosing: Pravastatin

A

40-80 mg

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25
Adverse Effects: Pravastatin
musculoskeletal pain upper respiratory tract infection
26
Monitoring Parameters: Pravastatin
lipid panel hepatic transaminase levels
27
Brand Name: Simvastatin
Zocor
28
Dosing: Simvastatin
20-40 mg
29
Adverse Effects: Simvastatin
-atrial fibrillation -edema -eczema -abdominal pain -constipation -gastritis -nausea -cystitis -increased serum transaminases -headache -vertigo -increased creatine phosphokinase in blood specimen -myalgia -bronchitis -upper respiratory infection
30
Monitoring Parameters: Simvastatin
lipid panel hepatic transaminase levels
31
Brand Name: Nitroglycerin
Nitrostat, Nitromist, Minitran
32
Dosing: Nitroglycerin
SL Tab: 0.3-0.6 mg prn repeat q5min 1-3 times SL Spray: 0.4 mg/spray prn repeat q5min 1-3 times SL Powder: 0.4 mg/pack prn repeat q5min 1-3 times IV: 10 mcg/min IV Patch: 0.2 - 0.4 mg/hour once daily, on for 12-14 hours, off for 10-12 hours
33
Adverse Effects: Nitrates
headache hypotension facial flushing reflex tachycardia
34
Monitoring Parameters: Nitrates
Blood pressure Heart Rate
35
Brand Name: ISMN
Monoket
36
Dosing: ISMN
Immediate Release: 20 mg BID (8 am 3pm) Extended Release (SR): 30-60 mg once daily, may titrate to 120 mg
37
Brand Name: ISDM
Dilatrate-SR, Isordil Titradose
38
Dosing: ISMD
Immediate Release: 5-20 mg BID/TID initially, max 10-40mg BID/TID (14 hour nitrate free period) Extended Release: 40-160 mg/day (18 hour nitrate free period)
39
Brand Name: Ranolazine
Ranexa
40
Dosing: Ranolazine
500 mg BID (max 1000 mg BID)
41
Adverse Effects: Ranolazine
Constipation Nausea Dizziness Headache
42
Monitoring Parameters: Ranolazine
QT interval
43
Brand Name: Bisoprolol
Zebeta
44
Dosing: Bisoprolol
5-10 mg QD
45
Monitoring Parameters
BP HR (50-60 bpm)
46
Brand Name: Nebivolol
Bystolic
47
Dosing: Nebivolol
5 mg daily (max: 40 mg daily)
48
Brand Name: Propranolol
Inderal
49
Dosing: Inderal
80-160 mg daily
50
Brand Name: Nifedepine
Procardia, Adalat, Cardene
51
Dosing: Nifedepine
10-20 mg TID 20-40 mg TID (Cardene)
52
Brand Name: Felodipine
Plendil
53
Dosing: Felodipine
5-10 mg daily
54
Adverse Effects: DHP CCBs
hypotension flushing headache dizziness peripheral edema reflex tachycardia
55
Monitoring Parameters: DHP CCBS
edema blood pressure
56
Brand Name: Verapamil
Calan, Isopin
57
Dosing: Verapamil
Immediate Release: 60-90 mg TID-QID Extended Release: 240 mg daily
58
Adverse Effects: Non DHP CCBs
reduced myocardial contractility (V>D) bradycardia AV Block (V>D) Hypotension Flushing Headache Dizziness Constipation (V>D)
59
Monitoring Parameters: Non DHP CCBs
constipation heart rate blood pressure
60
Brand Name: Diltiazem
Cardiazem
61
Dosing: Diltiazem
80-120 mg TID SR: 60-120 mg BID CD: 180-360 mg XR: 180-540 mg ER: 180-360 mg
62
Brand Name: Dapagliflozin
Farxiga
63
Dosing: Dapagliflozin
5 mg PO QD (eGFR > 45) max dose: 10 mg PO QD
64
Brand Name: Empagliflozin
Jardiance
65
Dosing: Empagliflozin
10 mg PO QD (eGFR > 30) max dose: 25 mg PO QD
66
Adverse Effects: SGLT-2
-UTIs -genital fungal infections -increased urination -hypotension -hyperkalemia -increased cholesterol -diabetic ketoacidosis -bone fractures and decreased bone mineral density (canagliflozin) -acute kidney injury (canagliflozin and dapagliflozin)
67
Monitoring Parameters: SGLT-2s
-use with caution in patients who have potential for dehydration or hypotension or taking diuretics, NSAIDs, or ACE inhibitors/ARBs (canagliflozin and dapagliflozin) -preventative foot care and monitor for new pain, tenderness, sores, ulcers, and infections in legs and feet -use with caution in patients with prior amputations, peripheral vascular disease, neuropathy, and diabetic foot ulcers -monitor signs and symptoms of tenderness, redness, or swelling of genitals or area from genitals to back of rectum, and fever, fatigue, and malaise
68
Brand Name: Hydralazine
BiDil
69
Dosing: Hydralazine
25 mg TID in combination with ISDN (target: 75 mg or 100 mg TID)
70
Adverse Effects: Hydralazine
palpitations tachycardia chest pain GI side effects headache hematologic dyscrasias hepatotoxicity lupus-like syndrome/rash fluid retention
71
Monitoring Parameters: Hydralazine
Blood pressure HR CBC antinuclear antibody titer
72
Brand Name: Furosemide
Lasix
73
Dosing: Furosemide
initial dose: 20-40 mg qd or bid Maintenance: 20-160 mg qd or bid
74
Adverse Effects: Loop Diuretics
AKI Fluid/electrolyte imbalance hypersensitivity ototoxicity
75
Monitoring Parameters: Loop Diuretics
BP Electrolytes Kidney Function Fluid I/Os
76
Brand Name: Bumetadine
Bumex
77
Dosing: Bumetadine
Initial Dosing: 0.5-1 mg qd or bid Maintenance: 1-2 mg QD or BID
78
Brand Name: Torsemide
Soaanz
79
Dosing: Torsemide
Initial: 10-20 mg Maintenance: 10-80 mg
80
Brand Name: HCTZ
Esidrix, Hydrodiuril
81
Dosing: HCTZ
initial: 25 mg/day maintenance: 100 mg/day
82
Brand Name: Clorthalidone
Thalitone
83
Dosing: Clorthalidone
12.5-25 mg/day maintenance: 50 mg/day
84
Adverse Effects: Thiazides
hypokalemia hypomagnesemia hypercalcemia hyperuricemia hyperglycemia hyperlipidemia sexual dysfunction increase in triglycerides/cholesterol
85
Monitoring Parameters: Thiazides
BP Fluid I/O Serum Electrolytes Kidney Function
86
Brand Name: spironolactone
Aldactone
87
Dosing: Spironolactone
Initial: 12.5 mg qd Maintenance: 50 mg/day
88
Adverse Effects: spironolactone
hyperkalemia hyponatremia gynecomastia (aldosterone)
89
Monitoring Parameter:
electrolytes potassium blood pressure
90
Brand Name: Candesartan
Atacand
91
Dosing: Candesartan
initial: 4-8 mg qd target: 32 mg qd
92
Brand Name: Digoxin
Digitek
93
Dosing: Digoxin
0.125-0.25 mg once daily
94
Monitoring Parameters: Digoxin
Serum Concentration 0.5 - <0.9 ng/mL HR Rhythm electrolytes
95
Adverse Events: Toxicity
toxicity
96

PHRM 841 (2 decks)

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