II. Principles of Pharmaceutical Sciences: Chemical Kinetics and Solution dosage form. Flashcards

1
Q

The time-required for one-half of the material to disappear or the time required for the concentration to reach 50% its initial value is defined as:

A. Half-life
B. Shelf-life
C. First order-life
D. Zero order-life

A

A. Half-life

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2
Q

Which solution dosage form’s administration is invade and should be isotonic, pyrogens-free and particulates free?

A. Dehydration solution
B. Topical solution
C. Ophthalmic solution
D. Parenteral solution

A

D. Parenteral solution

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3
Q

c. Percent and type of alcohols in 180 proof USP alcohol is:

A. 50% Ethanol
B. 70% Isopropyl alcohol
C. 98.5% Ethanol
D. 95% Ethanol

A

D. 95% Ethanol

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4
Q

Penicillin V Potassium is an example of:

A. Colonic lovage solution
B. Dry mixture for solution
C. Oral dehydration solution
D. Wet mixture of solution

A

B. Dry mixture for solution

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5
Q

An alcoholic or hydro alcoholic solutions prepared from the vegetable materials or chemical substances with 15-80% alcohol is defined as:

A. Elixir
B. Tincture
C. Syrups
D. Suspension

A

B. Tincture

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6
Q

Which of the following solvents, is prepared by mixing equal (50%) volumes of Alcohol, USP, and Purified Water, USP?

A. Alcohol, USP
B. Dehydrated Alcohol
C. Diluted Alcohol, NF
D. Rubbing alcohol

A

C. Diluted Alcohol, NF

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7
Q

The initial dose and maintenance dose of digoxin in digoxin elixir is:

A. 1.5mg and 0.5mg respectively
B. 5.0mg and 7.5gm
C. 5.0 and 1.5mg

A

A. 1.5mg and 0.5mg respectively

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8
Q
Which of the following solution is same as syrup but less sweet and less viscous?

A. Fluidextract
B. Tincture
C. Elixir
D. Spirit
A

C. Elixir

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9
Q

Which solution is used to prevent acidosis?

A. Sodium citrate and citric acid oral solution
B. Magnesium citrate oral solution
C. Sodium bicarbonate oral solution

A

A. Sodium citrate and citric acid oral solution

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10
Q

Which of the following method is not to purify water?

A. Ion exchange
B. Distillation
C. Crenation

A

C. Crenation

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11
Q

A saturated aqueous solution of volatile oils or other aromatic drug substances is:

A. Aromatic water
B. Tincture
C. Elixir
D. Syrup

A

A. Aromatic water

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12
Q

Which alcohol ingredient is controlled by IRS?

A. USP Alcohol
B. Rubbing Alcohol
C. Diluted Alcohol
D. sopropyl rubbing Alcohol

A

B. Rubbing Alcohol

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13
Q

Percent, type and proof of USP Dehydrated alcohol is:

A. 95%, Ethyl alcohol 180 proof
B. 99.5% Ethyl alcohol 200 proof
C. 50% Methyl alcohol 100 proof
D. 70% Isopropyl alcohol 140 Proof

A

B. 99.5% Ethyl alcohol 200 proof

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14
Q

Most common preservatives used in syrup is:

A. Benzocaine 1% to 3%
B. Benzoic acid 0.1% to 0.2%
C. Isopropyl alcohol 45% to 50%
D. USP Alcohol 70% to 90%

A

B. Benzoic acid 0.1% to 0.2%

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15
Q

If the rate of a reaction is constant and independent of concentration of any reactant is:

A. Zero order reaction
B. Second order reaction
C. First order reaction
D. Pseudo order reaction

A

A. Zero order reaction

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16
Q

Which is an alcoholic solution of aromatic or volatile drug substances?

A. Essence
B. Fluidextract
C. Aromatic water
D. Syrup

A

A. Essence

17
Q

Penicillin V Potassium is an example of:

A. Otic solution
B. Ophthalmic solution
C. Oral solution
D. Dehydration solution

A

C. Oral solution

18
Q

Pharmaceutical solution that uses viscous materials such as polyethylene glycol (PEG), glycerin and propylene glycol is:

A. Opthalmic solution
B. Rectal solution
C. Oral solution
D. Otic solution

A

D. Otic solution