IM1: Overview of immunology

Question 1

What are the 2 arms of immune response?

Answer 1

Innate & adaptive.

Question 2

What are the characteristics of innate immune response?

Answer 2

• Non-specific
• Very rapid
• Present in all animals
• Has both physical & blood-borne barriers
• No memory

Question 3

What are the characteristics of adaptive immune response?

Answer 3

• Specific
• Slower than innate
• Recognises specific pathogens via receptors
• Found in vertebrates.
• Has memory
• Has a cellular component (cytokines) and a humoral component (antibodies)

Question 4

What is the difference between cell-mediated and humoral immune response?

Answer 4

Cell-mediated immune response uses cytokines & kills pathogens while humoral immune response uses antibodies & chemicals.

Question 5

When the pathogen enters via tissues, where does the immune response come from?

Answer 5

Lymph nodes that produce lymphocytes.

Question 6

When the pathogen enters via mucosa, where & how is the immune response produced?

Answer 6

From Mucosa-Associated Lymphoid Tissue (MALT) that recognises the pathogen & allows the pathogen to enter Peyer’s patch. Peyer’s patch is connected to the mesenteric lymph node so it can produce an immune response.

Question 7

When the pathogen via the blood where does the immune response come from?

Answer 7

Spleen