IMM 2 Innate immunity Flashcards
(37 cards)
Innate immunity functions and reactions?
inflamation can result from what?
is it good?
what happens normally?
when its not normal?
What causes infected area to be red and warm?
What causes swelling?
What do the immune cells do here?
what causes pain?
what other body reactoin?
Does innate responses work?
Inflammation and infection steps
what doesnt inflammation work well against?
What mediates the anti-viral response in the innate immune system.
how do innate immune cells recognize self vs. nonself?
- innate immuknity have the ability to discriminate between self and nonself
- basic mechanism involves receptors which recognize “pathogen assoctiated molecular patterns”
- PAMPS
- cell receptor recognizing PAMPs are termed “pattern recognition receptors”
- PRRs
what are the characteristics of PAMPs?
Some examples of PAMPs?
Properties of PRRs
Mannose receptor
Toll-like receptors
What are they what do they look for?
which TLRs are extracellular? which are intracellular?
Make chart of what TLRs combine or fight what?
quick overview of the signalling pathway of TLRs
Which TLRs for what type of foreign?
Overall role of TLRs
What does TLR activate in the end what do they cause?
what causes T-cell response?
TLR-4 action
What triggers inflammation?
PAMPs and DAMPs (damage associated molecular patterns)
What causes DAMPs?
What do DAMPs activate? what molecules do this?
Nod-like receptors
What do NLRs do specifically?
Where are secreted forms of IL1beta and IL-18 produced?`
inflammasome
