Immmune + Inflammation Questions Flashcards
Anitbody
-Y shaped protein produced and secreted by B cells
-Identfies pathogens
What are the five classes of antibodies?
igA
igD
igE
igG
igM
What is a leukocyte?
-another name for a white blood cell
Describe the immune system
A network of cells and prossess that that work together to protect body from disease
Leukocyte are the primary ______ cell of the immune system
Effector
What is the first layer of the immune system?
Skin and Mucous membrane
Where do cells start?
in bone marrow
What is the second line of defense?
the nonspecific/innate immunity
(NK cells, mast cells, eosiophils, basophils, phagocytic cells, dendritic cells, macrophages, neutrophils)
What is the third line of defense?
-The specific/adaptive immunity
(B cells and T cells)
the third line of defense has _____
memory
Describe the first line of defense
-physical barriers to prevent pathogen entry
-is mechanical,biological, and chemical
What is the problem with the first layer of defense?
any physical trauma or changes to these barriers allow for pathogen entry
What are the cells of innate immunity?
Basophil, eoinosphil, neutrophil, NK cell, macrophages, mast cells
Innate immune system
-Response is _______
-Does it have memory?
-what forms of life is it found in?
Response is NON SPECIFIC
Does NOT have memory
found in ALL forms in life
Adaptive immune system
-______&______ response
-exposure leads to _____
-found in what forms of life?
-pathogen and antigen response
-exposure leads to MEMORY
-found in jawed vertebras
Phagocyte (innate immune cell)
-A cell that eats pathogens up
which cells are phagocytes?
Macrophages, neutrophils, dendritic cells
Dendritic cellls
-professional Antigen Presenting Cells (APC)
-present external cells
-can activate adaptive immune system!!
Macrophages
-professional APCs
-produce complement and cytokines
-can activate adaptive immune system
neutrophils
circulate leukocytes (WBCs)
What is the most abundant WBC and the first responder?
Neutrophils
Mast cells
-in connective tissues and mucous membranes
-regulate the inflammatory response
Eosionphils and basophils
*related to neutrophils
-defend against parasites
What is an example of a compromised host cell that a NK cell would kill?
Cancer cells
