IMMS Flashcards
(26 cards)
Site of oxidative phosphorylation?
Mitochondria
Where does the Krebs cycle occur?
Matrix
On what membrane are the proteins involved in elactron transport ?
Inner membrane
Siet of protein synthesis
Rough Endoplasmic reticulum
3 types of fillament proteins
Microfilaments- Actin
Microtubules- Tublin protein
Intermediate filament- 6 types of protein
4 main catagories of protein
Transporters (Facilitated diffusion), Anchors (Desmosomes), Receptors, Enzymes
Homeostasis?
the maintenance of a constant internal environment
Osmolality?
The concentration of an osmotic solution, expressed in terms of osmoles
Oncotic pressure ?
form of osmotic pressure exerted by proteins, in blood pressure , tends to pull water in to circulatory system from interstitial fluid
Osmotic pressure?
pressure exerted by the flow of water through a semi permeable membrane separating two solutions with different concentrations of solute
What are the electrolytes?
Sodium: High hypernaturaemia, low hypnaruraemia
Pottasium: High hyperkalaemia, low hypokalaemia
Calcium: High hypercalaemia, low hypocalaemia
Action of co-enzymes?
Bind to active site with substrate, take part on reaction and are changed, recycled
How many chromosomes in a genome?
46 chromosomes
How chromosomes are made
Nucleosome (8 separate histone protein attached to DNA molecule), multiple nucleosome coil together + stack on top as chromatin ( a supercoil), coils again to create chromosome
Semi conservative=
DNA helix splits and one new strand is added to each new half. So DNA composed of a new one and an old one.
What does poly-A RNA do?
Edits the RNA removing the intron (non-coding bit0 and leaving the extron (coding section)
Polymorphism=
Benign mutation
Out-frame deletion causes
one base deletion, huge effect
In-frame deletion causes
one codon deletion
Non-sense deletion causes
a stop codon either at deletion site or later on in sequence
Mis-sense mutation causes
single base substitution ( so may change type of amino acid in protein), could also just be a polymorphism
What occurs in prometaphase ?
Nuclear membrane breaks down, chromosomes attach to microtubules that have invaded
Phenotype=
The appearance of an individual resulting from interaction of the environment and genome.
Genotype=
The genetic constitution of an individual