Immune Flashcards
(15 cards)
Function of Leukocytes (white blood cells)
Protection against bacteria, viruses, parasites, toxins, tumor cells. Can leave bloodstream to mount immune and/or inflammatory response
How do Leukocytes know where to go?
Chemotaxis- Signals released from infection site
Types of Leukocytes
Granulocytes (Neutro, Eosino, Basophiles) and agranulocytes (Lympho, monocytes)
Percentage ranking of types of Leukocytes
Never Let Monkeys Eat Bananas
Neutrophiles, Lympocytes, Monocytes, Eosinophiles, Basophiles
Types of Granulocytes
Neutrophils
Eosinophils
Basophils
Neutrophils
Granules contain hydrolytic enzymes and defensins- some antibiotic-like proteins, polymorphic leukocytes.
Phagocytes!!!- they ingest and destroy bacteria (ie acute infections like meningitis, appendictitis)
Eosinophiles
coarse, red granules, parasitic worms cannot be phagocytized but are surronded and release digestive enzymes
Basophils
Rarest WBCs, cytoplasmic granules contain histamine (vasodilator, makes blood vessels leaky and attracts other WBCs!!)
Types of agranulocytes
Lymphocytes (T cells and B cells)
Monocytes
Function of T cells
Act directly against virus-infected cells, tumor cells. Go to thalamus gland to get tested. Made in bone marrow
Function of B cells
Give rise to plasma cells that produce antibodies. Made and tested in bone marrow
Function of monocytes
Differentiate into macrophages
Innate defenses
Surface barriers and internal defenses (phagocytes, natural killer cells, inflammation, antimicrobial proteins, fever)
Adaptive defenses
Humorla immunity (b cells), cellular immunity (t cells)