Immune Modulators

Question 1

Immune Modulators Drug Names

Answer 1

Apremilast

Question 2

Immune Modulators Therapeutic Actions

Answer 2

• Block the release of various cytokines involved in the inflammatory response and activation of lymphocytes, decreasing immune activity
• Inhibit the secretion of proinflammatory cytokines and increase the secretion of anti-inflammatory cytokines from monocytes and have varying effects on cell proliferation.

Question 3

Immune Modulators Contraindications and Cautions

Answer 3

Contraindications:
• Pregnancy and lactation
• severe liver impairment

Question 4

Immune Modulators Adverse Effects

Answer 4

Unknown

Question 5

Immune Modulators:

Assessment

Answer 5

Assess:
Hx: Contraindications and cautions
Physical: vital signs, weight, temp, orientation and reflexes (baseline)
Labs: baseline ECG

Question 6

Immune Modulators:

Diagnosis

Answer 6

Dx:

• Acute pain: to CNS, GI and flu-like effects
• Risk for infection related to immune suppression
• Imbalanced nutrition: less than body requirements, related to nausea and vomiting
• Deficient knowledge: drug therapy

Question 7

Immune Modulators:

Implementation

Answer 7

Implementation:
• Arrange for laboratory tests before and periodically during therapy
• Administer the drug as indicated; instruct the patient and a significant other if injections are required
• Protect the patient from exposure to infections and maintain a strict aseptic technique for any invasive procedures
• Monitor nutritional status during therapy; provide small, frequent meals, mouth care, and nutritional consultation
• Instruct females in use of barrier contraceptives
• Suggest another method of feeding the baby
• Provide thorough patient teaching

Question 8

Immune Modulators:

Evaluation

Answer 8

Eval:
Response to the drug 
Adverse effects 
Effectiveness of comfort measures Compliance with the regimen
Effectiveness of the teaching plan