Immune signals

Question 1

B7/CD80

Answer 1

expressed on the surface of APCs

Question 2

CCR2 CCL2

Answer 2

analogous to IL-8 for macrophages

Question 3

CD15 + and CD16b+

Answer 3

Found on surface of neutrophils

Question 4

CD19 and CD21+

Answer 4

on surface of b cells

Question 5

CD14+ (TLR4)

Answer 5

found on surface of macrophages which binds to LPS

Question 6

CD16+ CD56+

Answer 6

On surface of NK cell

Question 7

CD19+ CD20+

Answer 7

on surface of B cell

Question 8

CD23

Answer 8

has high affinity acer. on surface of mast cell

Question 9

CS23a CD23b

Answer 9

Receptor for IgE that is found on mature B cells, activated macrophages, eosinophils, basophils, dendritic cells, mast cells

Question 10

CD25+ CD4+

Answer 10

expressed on surface of Tregs that function to inhibit self-reactive Th1 cells in periphery

Question 11

CD3+ CD4+

Answer 11

On surface of T helper cells

Question 12

CD3+ CD4+ CD25+ IL-10 TGF-B

Answer 12

on surface of Treg

Question 13

CD3+

Answer 13

on the surface of all types of T cells

Question 14

CD80

Answer 14

On dendritic cells

Question 15

GATA-1

Answer 15

required for terminal differentiation to eryhroid lineage

Question 16

GATA-3

Answer 16

required for development of t lymphocytes

Question 17

IFN-gamma

Answer 17

secreted by NK cells to activate macrophages

Question 18

IL-1, IL-12, IL-23

Answer 18

chemokine that call M1 macrophages to site of inflammation

Question 19

IL1, IL18

Answer 19

produced by NLRP3 inflammasome and causes potent inflammatory response. Capase-1 involvement

Question 20

IL1 TNF

Answer 20

increase expression of P and E selections on endothelium to cause “rolling leukocytes”

Question 21

IL1 TNF alpha and IL8

Answer 21

activate and call neutrophils

Question 22

IL8

Answer 22

Caller of the neutrophils

Question 23

IL10 TGFB

Answer 23

Chemokine that calls M2 macrophages to reduce inflammation

Question 24

IL10

Answer 24

Anti-inflammatory. secreted by microphones, dendritic cells, and Tregs

Question 25

IL12, IL15, Type 1 IFN

Answer 25

activate natural killer cells

Question 26

IL4 and IL5

Answer 26

important for immunological response that involve IgE and eosinophils

Question 27

IL4, IL5, IL10

Answer 27

produced by Th2 cells

Question 28

IL4

Answer 28

leads to proliferation of IgE

Question 29

IL5

Answer 29

will cause eosinophilic deletion of helminth invasion

Question 30

IL4, IL13

Answer 30

Induces monocyte to become an M2 macrophage

Question 31

IFN a

Answer 31

Interferon that inhibits viral replication by inhibition of protein synthesis. Produced by leukocytes

Question 32

INF b

Answer 32

interferon that inhibits viral replication of protein synthesis. produced by fibroblast.

Question 33

LFA 1

Answer 33

Found on neutrophils, macrophages, b cells and T cells. Binds to ICAM and is important in rolling response.

Question 34

VLA 4

Answer 34

expressed on the surface of lymphoid progenitor cell that adheres to VCAM 1. promotes about interaction between the stem cell factor and kit leading to proliferation.