Immune System Flashcards

(52 cards)

1
Q

What is humanities deadliest disease?

A

smallpox

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2
Q

How does immunization work?

A

antigens are artificially introduced to induce adaptive immunity

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3
Q

Define inoculation

A

the act of immunizing someone against a disease by introducing material

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4
Q

What is similar between immunological memory and immunization?

A

they expose the organism to antigens

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5
Q

Define clonal selection

A

the process by which body produces B and T cells in response to infections

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6
Q

What is an “inactivated” vaccine?

A

the vaccine contains a dead virus

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7
Q

What is a “live” vaccine?

A

the vaccine contains an attenuated (reduced) virus

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8
Q

What is “recombinant” vaccine?

A

the vaccine contains viral antigens

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9
Q

What is an “mRNA” vaccine?

A

the vaccine contains an mRNA code for the viral antigen

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10
Q

Define innate immunity

A

the first line of defense against pathogens that does not involve infection of the host

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11
Q

What kind of immunity do invertebrates exhibit?

A

strictly innate immunity

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12
Q

What is a hemocyte?

A

an immune system blood cell, especially in invertebrates

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13
Q

What kind of immunity do vertebrates exhibit?

A

innate AND adaptive immunity

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14
Q

Define adaptive immunity

A

the immune response that occurs after infection occurs

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15
Q

What kind of immunity is skin, mucus, and acidity?

A

innate immunity

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16
Q

What are phagocytic cells?

A

cells that arrive at the infection and boost immune responses

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17
Q

What is phagocytosis?

A

the process by which a phagocytic cell uses vacuoles to digest pathogens

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18
Q

What are the four functions of a macrophage?

A
  1. phagocytosis
  2. stimulates other immune cells
  3. removes dead cells
  4. secretes cytokines
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19
Q

Three types of phagocytic cells

A

macrophage, neutrophil, and dendritic cell

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20
Q

What are the three functions of a neutrophil cell?

A
  1. phagocytosis
  2. extracellular traps
  3. mediate inflammation
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21
Q

What are the two functions of a dendritic cell?

A
  1. phagocytosis
  2. displays antigens on its surface to boost immune response
22
Q

What does a mast cell release?

23
Q

What is the purpose of histamines?

A

they trigger the bodies response to inflammation, including dilating blood vessels

24
Q

Is systemic inflammation innate or adaptive immunity?

25
What is systemic inflammation?
inflammation throughout the whole body triggered by severe infections or tissue damage
26
What is septic shock?
whenever an infection causes the body to go into shock; organs fail and the heart slows
27
What is adaptive immunity?
pathogen-specific responses to infection
28
Are lymphocytes innate or adaptive immunity?
adaptive
29
What are lymphocytes?
white blood cells called leukocytes that is found in the blood and lymph tissue
30
What kind of cell are B and T cells?
lymphocytes
31
What is an antigen?
a toxin or foreign substance that triggers an immune response which produces antibodies
32
What is an antigen receptor?
a protein anchored to the B or T cell membrane that bind to a pathogen's epitopes
33
What are epitopes?
the part of the antigen to which the antigen receptor/antibody attaches itself
34
How are B cells activated?
they bind the antigens on the surface of the pathogen's membrane
35
What is clonal selection?
the process by which antigens trigger lymphocytes to produce antibodies
36
What is adaptive immunity?
pathogen-specific responses to infection
37
how are T cells activated?
their receptors are can only bind to antigens presented by infected and immune cells
38
What do effector cells do?
secrete antibodies
39
What do memory immune cells do?
store antibodies an an insurance policy
40
Define immunological memory
long-term protection against previous infections
41
What is the primary response of the immune system?
the initial response to a pathogen
42
What is the secondary response of the immune system?
the response to a subsequent exposure
43
What is a helper T cell's function?
to formally initiate humoral and cell-mediated immunity
44
Define humoral immunity
the production of pathogen-specific antibodies by B cells
45
What is neutralization in humoral immunity?
antibodies attach to the antigens of a virus preventing it from binding to a host cell
46
What is opsonization in humoral immunity?
antibodies promote phagocytosis of the virus by macrophages and neutrophils
47
What is the complement system in humoral immunity?
compliment proteins attach to antibodies which form pores in the pathogen's membrane
48
Define cell mediated immunity
when helper T cells and antigen presenting cells activate cytotoxic T cells
49
What is an MHC molecule?
the molecule that presents an antigen on the surface of a body cell
50
What are cytotoxic T cells?
cells that secrete toxic proteins directly into the infected host cells
51
What causes allergies?
exaggerated reaction to antigens (allergens) that activate mast cells to produce histamine
52
What is an autoimmune disease?
when the immune system fails to recognize self antigens