Immune system Flashcards

1
Q

The immune system consists of what…

A

tissues, cells, and organs that fight off illness and disease

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2
Q

The immune system is composed of both ________ and _________ defenses.

A

innate, and adaptive

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3
Q

Innate defenses are _______.

A

nonspecific

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4
Q

Adaptive defenses are ________.

A

specific

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5
Q

What is a pathogen?

A

a foreign invader

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6
Q

Innate immune functions occur _____________.

A

the same way every time, regardless of the type or number of pathogens that are present

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7
Q

Innate defenses include both ____________.

A

a first and second line of defense

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8
Q

First line of defense includes…..

A

both physical and chemical barriers (skin, mucous membranes, and digestive enzymes)

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9
Q

Second line of defenses include….

A

fever, inflammation, phagocytosis, natural killer cells, interferons, chemotaxis, and release of cytokines.

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10
Q

What is phagocytosis?

A

engulfing of pathogens by white blood cells

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11
Q

Mild to moderate fevers benefit the body how?

A

by killing pathogens that grow better at a lower temperature

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12
Q

What are the four cardinal signs of inflammation?

A

redness, heat, swelling, and pain

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13
Q

What do natural killer cells do? Another name?

A

produce perforins that target cancer and virus cells, NK cells

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14
Q

What are perforins? What do they cause the cels to do?

A

pore forming protein, lyse

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15
Q

Lyse is another word for?

A

rupture

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16
Q

What are interferons?

A

the body’s response to a viral infection and prevent replication of the virus after 7 to 10 days. They also activate macrophages and NK cells

17
Q

What is chemotaxis?

A

the method by which the leukocytes respond to damaged body tissues

18
Q

What are cytokines?

A

chemical messengers that are released by damaged tissues.

19
Q

What is diapedesis?

A

the process of white blood cells squeezing through capillary slits in response to cytokines

20
Q

What do CAM’s do?

A

cellular adhesion molecules, guide the white blood cells to the site of damage or infection

21
Q

Adaptive responses are ……

A

the third line of defense, or the specific defenses

22
Q

Adaptive responses include…

A

both the humoral, or antibody mediated, and the cell mediated responses

23
Q

In the antibody mediated branch…..

A

antibodies are produced that are specific for the invading antigen

24
Q

What is a B cell?

A

types of lymphocytes or small leukocytes

25
Q

In antibody mediated branch the antigen binds to…..

A

B cells followed by binding with T-helper cells, which activates the B cells to produce antibodies

26
Q

In active immunity….

A

an individual receives a vaccine that stimulates an actual infection by a pathogen, stimulating the body to produce antibodies for future protection.

27
Q

In passive immunity…

A

an individual does not produce his or her own antibodies, but rather receives them directly from another source, such as mother to infant thru breastmilk.

28
Q

Once the immune system has produced antibodies against a pathogen…..

A

it is able to recognize that pathogen in the future and destroy it more effectively.

29
Q

In cell mediated immunity….

A

T cells are primarily responsible for recognizing non self cells

30
Q

What is a T cell…

A

a lymphocyte that triggers the action of other lymphocytes

31
Q

What is the 3 step process of cell mediated immunity?

A

macrophages capture the non self cell, a T helper cell binds to it and secretes a cytokine that signals the cytotoxic T cell. The cytotoxic T cell responds through chemotaxis and actively destroys the non self cell.