Immunity Flashcards

1
Q

Immune cells for intracellular pathogens infecting individual cells

A

T cells

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2
Q

Immune cells for extracellular pathogens dividing outside cells

A

B cells

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3
Q

Key mediator of immunity that internalizes pathogens and degrade them

A

Phagocytes

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4
Q

Key mediator of immunity that have specific receptors that recognize pathogens

A

Lymphocytes

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5
Q

Two essential features of adaptive immune response

A

Specific and Memory

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6
Q

Cells thay recognize intact antigen

A

B cells

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7
Q

Cells that recognize Ag fragments displayed on the surface of APC cells

A

T cells

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8
Q

Two phases of immune response

A

Ag recognition
Ag eradication

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9
Q

A response to tissue damage resulting to phagocytes and Ag destruction

A

Inflammation

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10
Q

The sum total of the defense mechanisms of the human bbody to resist infectious disease

A

Immunity

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11
Q

Non-specific immunity

A

Innate/Natural immunity

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12
Q

Specific immunity

A

Adaptive/Acquired immunity

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13
Q

1st line of defense

A

External components
Physical and biochemical barriers

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14
Q

2nd line of defense

A

Internal components
Cellular and fluid components

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15
Q

3rd line of defense

A

Cellular immunity (T cells)
Humoral immunity (B cells)

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16
Q

Natural or Acquired:
Innate/Non-specific

A

Natural

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17
Q

Natural or Acquired:
Specifc/Adaptive

A

Acquired

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18
Q

Natural or Acquired:
Toll-like receptors

A

Natural

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19
Q

Natural or Acquired:
B-cell receptor

A

Acquired

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20
Q

Natural or Acquired:
Protection by natural means

A

Natural

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21
Q

Natural or Acquired:
Ab production

A

Acquired

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22
Q

Natural or Acquired:
Present at birth

A

Natural

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23
Q

Natural or Acquired:
Not present at birth

24
Q

Natural or Acquired:
Uniform response

25
Natural or Acquired: Diverse response
Acquired
26
Natural or Acquired: Lacks memory
Natural
27
Natural or Acquired: With memory
Acquired
28
Natural or Acquired: Effect: Rapid/Immediate
Natural
29
Natural or Acquired: Effect: Long term/Gradual
Acquired
30
Natural or Acquired: Response Time: Short Duration
Natural
31
Natural or Acquired: Response Time: Long Duration
Acquired
32
1st line of defense: Physical barriers
Intact skin Mucus membrane Cilia Cough reflux
33
2nd line of defense: Cellular components
Phagocytic cells Eosinophils Basophils and mast cells APCs NK cells
34
1st line of defense: Biochemical secretions
Lysozyme Lactic acid Sebum Earwax
35
2nd line of defense: Humoral components
Complement Cytokines Lysozyme Properdin Betalysin
36
3rd line of defense: Cellular components
Specialized lymphocytes T cells B cells Plasma cells APCs
37
3rd line of defense: Humoral components
Antibodies Cytokines Complements
38
Active immunity Substance introduced: Ab production: Immunity: Immune response:
Antigen Done by the body Long term Slow
39
Passive immunity Substance introduced: Ab production: Immunity: Immune response:
Antibody Not done by the body Short term Rapid/immediate
40
Natural active immunity
Actual infection
41
Natural passive immunity
Pregnancy Colostrum
42
Artificial active immunity
Smallpox Bacillus calmete guerin for M. tb Cholera and typhoid fever Toxoid for C. tetani Poliovirus
43
Artificial passive immunity
Anti-rabies HBIg Rhogam
44
The process by which powder form of smallpox scabs or lesions was inhaled by affected individuals in order to produce protection against the smallpox disease
Variolation
45
The process by which a material from cowpox lesions was injected to individuals with smallpox to develop immunity against it
Vaccination
46
The process by which a less infectious form of an agent is produced through heat, aging, or chemical means
Attenuation
47
The phenomenon in which exposure to one agent produces protection against another agent
Cross-immunity
48
Cellular Immunity Mechanism:
Cell-mediated
49
Cellular Immunity Cell type:
T cells
50
Cellular Immunity Mode of action:
Cytokine
51
Cellular Immunity Purpose:
Defense against viral/fungal infections (Intracellular)
52
Cellular Immunity Remarks:
Delayed hypersensitivity
53
Humoral immunity Mechanism:
Humoral-mediated
54
Humoral immunity Cell type:
B cells
55
Humoral immunity Mode of action:
Antibodies
56
Humoral immunity Purpose:
Defense against bacterial infection (Extracellular)
57
Humoral immunity Remarks:
Antibody dependent cellular cytotoxicity