Immunizations

Question 1

IgA

Answer 1

Mucous, tears, breastmilk

Question 2

IgD

Answer 2

Part of B cell receptor. Activates basophils and mast cells

Question 3

IgE

Answer 3

Protects against parasitic worms. Responsible for allergic reactions

Question 4

IgG

Answer 4

Secreted by plasma cells. Can cross placenta

Question 5

IgM

Answer 5

Early stages of immunity

Question 6

Passive immunity

Answer 6

Transfer of immunities via antibodies from person to person. Maternal antibody to infant. Wanes 4-12 months after birth

Question 7

Active immunity

Answer 7

Stimulation of own immune system. Relies on immunologic memory. Occurs from natural infection or vaccination

Question 8

Live attenuated vaccines

Answer 8

Contains live, weakened organisms

MMR, varicella, polio (sabin) adenovirus, influenza (inhaled), rotavirus, rotavirus

Question 9

Positives and negatives of live attenuated vaccines

Answer 9

single dose provides long-lasting immunity. Contraindicated in pregnancy and immunocompromised; adverse reactions similar to actual disease

Question 10

Whole inactivated vaccines

Answer 10

Hep A, Rabies, Influenza (IM), whole cell pertussis

Question 11

Positive and negatives of inactivated vaccines

Answer 11

Safe in pregnancy and immune compromised states.

Multiple doses or boosters needed

Question 12

Fractional inactivated vaccines

Answer 12

Portion of pathogen

Polysaccharide vaccines like PPV23, acellular pertussis, meningitis, influenza, hep B, HPV

Question 13

Toxoids

Answer 13

Inactivated bacterial toxins

Tetanus, diphtheria

Question 14

Adjuvants

Answer 14

Substance that enhances immune response to the antigen. Aluminum is the only approved adjuvant. Used in Hep B/A, DTaP, DT, Hib, HPV

Question 15

Pediarix

Answer 15

DTaP, Hep B, IPV

*we always give the Hep B vaccine in the newborn (pediatric) nursery

Question 16

Proquad

Answer 16

MMR + varicella

Question 17

Kinrix

Answer 17

DTaP + IPV

Question 18

Pentacel

Answer 18

DTaP+IPV+Hib

*Think Pentagon is like a like Hub (HiB)

Question 19

Comvax

Answer 19

Hib + HepB

Question 20

Twinrix

Answer 20

Hep A and Hep B

Question 21

True or false

Shortening the interval between doses does not interfere with immune response

Answer 21

False. It does. However, lengthening the interval does not diminish effectiveness.

Question 22

True or false: A immunocompromised patient can receive an inactivated vaccine

Answer 22

true

Question 23

True or False. You can’t receive a vaccine if you are breastfeeding, need TB skin testing, or are getting to many vaccines at one time

Answer 23

False

Question 24

What trimester should a pregnant person receive the TDaP vaccine

Answer 24

3rd trimester

Question 25

List some people who should not be given a LAIV

Answer 25

Asplenia, HIV, immunocompromised (or close contacts), cochlear implant, those who received influenza antiviral medication in past 48 hours, previous serious reaction to influenza vaccine

Question 26

CD4 count has to be above this to receive the MMR

Answer 26

200 for at least 6 months