Immuno - Immune Responses (Autoantibodies & associated disorders)

Question 1

With what disorder is Anti-ACh receptor associated?

Answer 1

Myasthenia gravis

Question 2

With what disorder is Anti-basement membrane associated?

Answer 2

Goodpasture syndrome

Question 3

With what disorder is Anti-cardiolipin, lupus anticoagulant associated?

Answer 3

SLE, antiphospholipid syndrome

Question 4

With what disorder is Anticentromere associated?

Answer 4

Limited scleroderma (CREST syndrome)

Question 5

With what disorder is Anti-desmoglein associated?

Answer 5

Pemphigus vulgaris

Question 6

With what disorder is Anti-dsDNA, anti-Smith associated?

Answer 6

SLE

Question 7

With what disorder is Anti-glutamate decarboxylase associated?

Answer 7

Type 1 diabetes mellitus

Question 8

With what disorder is Anti-hemidesmosome associated?

Answer 8

Bullous pemphigoid

Question 9

With what disorder is Antihistone associated?

Answer 9

Drug-induced lupus

Question 10

With what disorder is Anti-Jo-1, anti-SRP, anti-Mi-2 associated?

Answer 10

Polymyositis, dermatomyositis

Question 11

With what disorder is Antimicrosomal, antithyroglobulin associated?

Answer 11

Hashimoto thyroiditis

Question 12

With what disorder is Antimitochondrial associated?

Answer 12

Primary biliary cirrhosis

Question 13

With what disorder are Antinuclear antibodies associated?

Answer 13

SLE, nonspecific

Question 14

With what disorder is Anti-Scl-70 (anti-DNA topoisomerase I) associated?

Answer 14

Scleroderma (diffuse)

Question 15

With what disorder is Anti-smooth muscle associated?

Answer 15

Autoimmune hepatitis

Question 16

With what disorder is Anti-SSA, anti-SSB (anti-Ro, anti-La) associated?

Answer 16

Sjogren syndrome

Question 17

With what disorder is Anti-TSH receptor associated?

Answer 17

Graves disease

Question 18

With what disorder is Anti-U1 RNP (ribonucleoprotein) associated?

Answer 18

Mixed connective tissue disease

Question 19

With what disorder is c-ANCA (PR3-ANCA) associated?

Answer 19

Granulomatosis with polyangitis (Wegener)

Question 20

With what disorder is IgA antiendomysial, IgA anti-tissue transglutaminase associated?

Answer 20

Celiac disease

Question 21

With what disorder is p-ANCA (MPO-ANCA) associated?

Answer 21

Microscopic polyangitis, Churg-Strauss syndrome

Question 22

With what disorder is Rhematoid factor (antibody, most commonly IgM, specific to IgG Fc region), anti-CCP associated?

Answer 22

Rheumatoid arthritis

Question 23

With what autoantibody is Myasthenia gravis associated?

Answer 23

Anti-ACh receptor

Question 24

With what autoantibody is Goodpasture syndrome associated?

Answer 24

Anti-basement membrane

Question 25

With what autoantibody(-ies) is SLE, antiphospholipid syndrome associated?

Answer 25

Anti-cardiolipin, lupus anticoagulant

Question 26

With what autoantibody is Limited scleroderma (CREST syndrome) associated?

Answer 26

Anticentromere

Question 27

With what autoantibody is Pemphigus vulgaris associated?

Answer 27

Anti-desmoglein

Question 28

With what (specific) autoantibody(-ies) is SLE associated?

Answer 28

Anti-dsDNA, anti-Smith

Question 29

With what autoantibody is Type 1 diabetes mellitus associated?

Answer 29

Anti-glutamate decarboxylase

Question 30

With what autoantibody is Bullous pemphigoid associated?

Answer 30

Anti-hemidesmosome

Question 31

With what autoantibody is Drug-induced lupus associated?

Answer 31

Antihistone

Question 32

With what autoantibody(-ies) is Polymyositis, dermatomyositis associated?

Answer 32

Anti-Jo-1, anti-SRP, anti-Mi-2

Question 33

With what autoantibody is Hashimoto thyroiditis associated?

Answer 33

Antimicrosomal, antithyroglobulin

Question 34

With what autoantibody is Primary biliary cirrhosis associated?

Answer 34

Antimitochondrial

Question 35

With what autoantibody is SLE, nonspecific associated?

Answer 35

Antinuclear antibodies

Question 36

With what autoantibody is Scleroderma (diffuse) associated?

Answer 36

Anti-Scl-70 (anti-DNA topoisomerase I)

Question 37

With what autoantibody is Autoimmune hepatitis associated?

Answer 37

Anti-smooth muscle

Question 38

With what autoantibody is Sjogren syndrome associated?

Answer 38

Anti-SSA, anti-SSB (anti-Ro, anti-La)

Question 39

With what autoantibody is Graves disease associated?

Answer 39

Anti-TSH receptor

Question 40

With what autoantibody is Mixed connective tissue disease associated?

Answer 40

Anti-U1 RNP (ribonucleoprotein)

Question 41

With what autoantibody is Granulomatosis with polyangitis (Wegener) associated?

Answer 41

c-ANCA (PR3-ANCA)

Question 42

With what autoantibody is Celiac disease associated?

Answer 42

IgA antiendomysial, IgA anti-tissue transglutaminase

Question 43

With what autoantibody is Microscopic polyangitis, Churg-Strauss syndrome associated?

Answer 43

p-ANCA (MPO-ANCA)

Question 44

With what autoantibody(-ies) is Rheumatoid arthritis associated?

Answer 44

Rheumatoid factor (antibody, most commonly IgM, specific to IgG Fc region), anti-CCP