Immunodeficiencies Flashcards
(12 cards)
ataxia, telangiectasias, sinopulmonary infections
ataxia-telangiectasias
-increased sinopulmonary infections due to IgA deficiency
oculocutaneous albinism, pyogenic infections, progressive neurological dysfunction
Chediak-Higashi syndrome
severe bacterial and fungal infections, granuloma formation
Chronic granulomatous disease
congenital heart disease, dysmorphic facies, hypocalcemia
Di-George syndrome
severe bacterial and viral infections in infancy, chronic diarrhea, mucocutaneous candidiasis
Severe combined immunodeficiency
recurrent Neisseria infection
Terminal complement deficiency
recurrent infections that worsen with age, easy bleeding, eczema
Wiskott-Aldrich syndrome
NADPH oxidase deficiency
Chronic granulomatous disease
Immunoglobulin gene rearrangement impairment
hyper-IgM syndrome
defect in T-cell IL-2 R
SCID
epithelial cell Cl channels defective, respiratory infections, infertility
CF
C1 complement component deficiency
increased susceptibility to encapsulated bacteria (Strep pneumonia, H flu, Neisseria), predisposes to SLE
