Immunologic Disease

Question 1

Humoral Immunity response is?

Answer 1

takes place in body fluids (extracellular) and is concerned with antibody and compliment activities.

Question 2

Cell-mediated or cellular immunity is?

Answer 2

primarily intracellular, designed to destroy or contain cells that are recognized by the body as alien and harmful.

Question 3

When screening any client, what is the most important variable (part)?

Answer 3

the medical history

Question 4

A recent history of surgery may be indicative of?

Answer 4

bacterial or reactive arthritis, which requires immediate medical evaluation.

Question 5

Name a red flag to beware of when screening a client with conditions related to immune system dysfunction.

Answer 5

A positive family history for systemic inflammatory or related disorders (may be the only available red flag in this area)

Question 6

Symptoms of rheumatic disorders often include?

Answer 6

• soft tissue and/or joint pain
• stiffness
• swelling
• weakness
• constitutional symptoms
• Raynaud’s phenomenon
• sleep disturbances

Question 7

Inflammatory disorders such as RA and polymyalgia rheumatica, are marked (identified) by?

Answer 7

prolonged stiffness in the morning lasting more than 1 hour. stiffness is relieved with activity, but recurs after the person sits down and subsequently attempts to resume activity

Question 8

Arthropathy in the wrists and proximal small joints of the hands and feet is a typical feature of?

Answer 8

RA

Question 9

Generalized weakness in the absence of muscle disease is a common symptom of?

Answer 9

Immune system disorder

Question 10

If weakness is found in one limb without evidence of weakness elsewhere, a ________ disorder may be present.

Answer 10

neurologic

Question 11

Nail bed changes are indicative of underlying ___________ disease.

Answer 11

inflammatory

Question 12

Name the 4 Immunological disorders.

Answer 12

• Immunodeficiency disorder
• Hypersensitivity disorder
• Autoimmune disorder
• Immunoproliferative disorder

Question 13

Immunodeficiency Disorders are defined by?

Answer 13

When the immune system is underactive or hypoactive.

Question 14

Pain in the knees, hands, wrists, or elbows may indicate and ___________ disorder.

Answer 14

autoimmune

Question 15

True arthritis produces pain in active ROM, passive ROM or both?

Answer 15

both

Question 16

Limitations from tendonitis is much worse during _____ ROM.

Answer 16

active

Question 17

What important clues should we watch out for developing RA, when working with a client who in the first year postpartum.

Answer 17

• increased shoe size
• marked fatigue
• onset of symptoms

Question 18

Most common site of fracture for the client with RA or ankylosing spondylitis?

Answer 18

lower cervical spine.

Question 19

When is immediate medical attention needed when working with a client with immunologic disease?

Answer 19

• if exhibiting S&S of anaphylactic shock especially vocal hoarseness, difficult breathing, chest discomfort.
• if a new onset of joint pain with a recent history of surgery.
• if a joint has a dusky blue discoloration or erythema with tenderness, is a sign of a septic or infected joint.

Question 20

What are the guidelines physician referral when working with clients with immunologic disease?

Answer 20

• new onset of joint pain within 6 weeks of surgery (especially if constitutional symptoms, rash, skin lesions)
• symmetric swelling & pain in peripheral joints (early RA)
• development of progressive neurologic symptoms with in 1 to 3 weeks of previous infection or vaccination.
• evidence of spinal cord compression in anyone with RA, from stiffness to new onset of cervical laxity.
• incontinence in anyone with ankylosing spondylitis.

Question 21

Signs & Symptoms of RA include? (serious)

Question 22

How long do S&S of RA need to be present in-order to diagnose?

Answer 22

6 weeks

Question 23

What protein is responsible for triggering inflammation during a normal immune system response?

Answer 23

cytokines

Question 24

Therapeutic exercise for persons with RA should be?

Answer 24

• Specific functional training

- Exercises to prevent contractures and improve strength, flexibility, and cardiovascular fitness.

Question 25

CD4+/ T cell count of ?? to diagnose AIDS?

Answer 25

< 50

Question 26

With in first year of AIDS cognitive deficiencies.

Answer 26

AIDS Dementia Complex (more so skills like piano, not memory)

Question 27

Guillian-Barre syndrome is what?

Answer 27

like MS but off the PNS., it does resolve on its own.