immunology Flashcards
(17 cards)
1
Q
- function of immune system
A
- defence against microbes
- defence against - growth of tumour cells
- homeostasis- destruction of abnormal or dead cells
2
Q
what is the fucntion of innate immunity?
A
- initial prevention of infection until : -adaptive immune responses- are activated
- stimulating - adaptive immune responses- to be optimally effective against different types of microbes
3
Q
what are the 2 types of cells involved in innate immunity?
A
- myeloid origin cells
- lymphoid cells
4
Q
list out the cells in the myeloid origin?
A
- monocytes / macrophages
- dendritic cells
- neutrophils
- eosinophils
- mast cells
- basophils
5
Q
list out the cells involved in the lymphoid cells
A
- natural killer (NK) cells
- NK/T cells
6
Q
name the cells in granulocytes
A
- neutrophils
- eosinophils
- mast cells
- basophils
7
Q
what is the function of macrophages? (pc)
A
- phagocytosis of microorganisms
- cytokines secretion (TNF, IL-1,IL-6, IL-8, IL-12)
8
Q
what is a monocyte?
A
- young macrophage in blood
9
Q
example of macrophages
A
- alveolar macrophages
- histiocytes
- mesangial cells
- microgial cells
- kupffer cells
- osteoclasts
10
Q
where are dendrite cells found?
A
lymphatic tissue
11
Q
what is the fucntion of dendrite cells?
A
- present antigens to T cells
- initiate adaptive immune responses
12
Q
fucntion of neutrophils
A
- phagocytosis
- important in clearing bacterial infections
13
Q
fucntion of mast cells
A
- expulsion of parasites through release of granules
- involved in allergic responses
14
Q
what are the granules used for mast cells?
A
- histamine, leukotrienes, chemokines, cytokines
15
Q
fucntion of eosinophils
A
- killing ab-coated parasites through degranulation
- involved in allergic inflammation
16
Q
what is a basophil?
A
- cells killing cell that contains blue granules
17
Q
what do these blue granules in basophils contain?
A
- histamine, heparin, chemo tactic factor
