Immunology Flashcards Preview

MB 351 - Exam 4 > Immunology > Flashcards

Flashcards in Immunology Deck (14):
1

Why do we need an immune system? (3)

-Our bodies provide good nutrients and environment for microbes
-Allows our body to fight off and resist further infections
-Protects us from bacteria, viruses, fungi, parasites, and toxins

2

Innate Immune System (4)

-Fast acting
-General response
-Recognizes general features (e.g. fMet, LPS)
-No learning

3

Adaptive Immune System (4)

-Slow to respond
-Specific response
-Recognizes unique structures
-Uses memory and recall of defense

4

First line of defense for body (3)

-Skin
-Mucous membranes and secretions (e.g. acid)
-Normal microbiota

5

Second line of defense for body (4)

-Phagocytes
-Inflammation
-Fever
-Antimicrobial substances (e.g. lysozymes)

6

Third line of defense (2)

-Specialized lymphocytes (T and B cells)
-Antibodies

7

Cellular Content of Blood

-RBCs: non-nucleated, transport oxygen
-Platelets: used in clotting
-WBCs (Leukocytes): Nucleated immune cells

8

Types of WBCs (3)

-Monocytes
-Granulocytes
-Lymphocytes

9

Humoral Adaptive Immunity

-B cells help create antibodies that circulate in blood plasma and lymph to bind and mark foreign antigens for destruction

10

Cell-Mediated Adaptive Immunity

T cells interact with antigens on infected cells; T cells will then grow, divide, and produce T cells that recognize the pathogen; T cells then activate more macrophages, NK cells, antigen-specific cytotoxic T cells, and release of various cytokines

11

Acquiring a natural infection that initiates an adaptive immune response creates...

Natural Active Immunity

12

Intentional exposure to harmless antigen to induce antibody formation creates...

Artificial Immunity

13

Smallpox killed or maimed ___% of humankind

10

14

Variolation involved...

scratching a healthy person with pus from infected person with smallpox