Flashcards in Immunology Deck (27):
What vaccines are live attenuated?
Oral polio vaccine
- Chicken pox (varicella)
- Oral thyphoid
- Yellow fever
What vaccines are inactivated?
Whole cell typhoid
What vaccines are composed of organism components?
What is the basic reproduction number?
Number of cases one case will generate in that cases lifetime (til death/cure)
What is a contraindication for all vaccines?
Confirmed anaphylaxis to previous dose of same antigen/component
What are contraindications for live vaccines
- High dose steroids
Patients who have an egg allergy shouldn't receive what vaccines?
What are some other contraindications for vaccines?
Severe latex allergy
How should yellow fever and MMR be delivered?
>4 weeks apart
How should varicella and MMR vaccines be delivered?
If not given on the same day wait 4 weeks between the two
How should the Mantoux test and MMR be given?
If Mantoux given:
- Wait until result before MMR
- Give MMR is urgent protection needed
If MMR given:
- Wait at least 4 weeks before Mantoux
What immunisations are given at 2 months?
Diphtheria, Tetanus, Pertussis, Polio + Hib (DTap/lPV/Hib)
Pneumococcal conjugate (PCV)
At what ages is the MMR given?
Between 12-13 months of age
At 3 years 4 months of age
What vaccine is given annually between the ages of 2 and 17? How is it delivered?
- Nasal spray (one in each nostril)
At what age do girls receive the HPV vaccine?
What vaccines are given to 65 years olds?
Pneumococcal polysaccharide (given once)
Influenze (given annually)
What vaccine is given to 70 year old people?
What serogroup of meningococcal spp. has the worst outcomes?
Vaccines for which meningococcal serogroups do vaccines exist?
A, C, W, Y135 and B
What are common travel vaccines?
Hep A + C
Japanese B Encephalitis
What is disease control? What diseases does this apply to?
Reducing incidence to a locally acceptable level:
- Diarrhoeal disease
What is disease elimination? What disease does this apply to?
Reduce incidence to zero in an area:
- Neonatal tetanus
What is infection elimination? What diseases does this apply to?
Reducing incidence of infection of a specific agent in an area:
What is erradication? What diseases does this apply to?
Permanent worldwide reduction of incidence to zero:
What is extinction? What diseases does this apply to?
Agent no longer exists in nature or labs:
What can CYT009-GhrQb be used to treat? How does it work?
'Instructs' immune system to produce anti-ghrelin Ab response:
- Ghrelin is a peptide regulator of eating