Immunology Flashcards Preview

Year 2 - Child Health (DP) > Immunology > Flashcards

Flashcards in Immunology Deck (27):
1

What vaccines are live attenuated?

MMR
Oral polio vaccine
Others:
- Chicken pox (varicella)
- Influenza
- Rotavirus
- BCG
- Oral thyphoid
- Yellow fever
- Mantoux

2

What vaccines are inactivated?

Pertussis
Whole cell typhoid

3

What vaccines are composed of organism components?

Influenza
Pneumococcal
Diphtheria
Tetanus toxoid

4

What is the basic reproduction number?

Number of cases one case will generate in that cases lifetime (til death/cure)

5

What is a contraindication for all vaccines?

Confirmed anaphylaxis to previous dose of same antigen/component

6

What are contraindications for live vaccines

Immunosuppression:
- Primary
- Radiotherapy
- High dose steroids
- HIV
Pregnancy

7

Patients who have an egg allergy shouldn't receive what vaccines?

Yellow fever
Flu (live)

8

What are some other contraindications for vaccines?

Severe latex allergy
Acute/Evolving illness

9

How should yellow fever and MMR be delivered?

>4 weeks apart

10

How should varicella and MMR vaccines be delivered?

If not given on the same day wait 4 weeks between the two

11

How should the Mantoux test and MMR be given?

If Mantoux given:
- Wait until result before MMR
- Give MMR is urgent protection needed
If MMR given:
- Wait at least 4 weeks before Mantoux

12

What immunisations are given at 2 months?

Diphtheria, Tetanus, Pertussis, Polio + Hib (DTap/lPV/Hib)
Pneumococcal conjugate (PCV)
Rotavirus

13

At what ages is the MMR given?

Between 12-13 months of age
At 3 years 4 months of age

14

What vaccine is given annually between the ages of 2 and 17? How is it delivered?

Influenza:
- Nasal spray (one in each nostril)

15

At what age do girls receive the HPV vaccine?

12-14 years

16

What vaccines are given to 65 years olds?

Pneumococcal polysaccharide (given once)
Influenze (given annually)

17

What vaccine is given to 70 year old people?

Shingles

18

What serogroup of meningococcal spp. has the worst outcomes?

B

19

Vaccines for which meningococcal serogroups do vaccines exist?

A, C, W, Y135 and B

20

What are common travel vaccines?

Hep A + C
Typhoid
Rabies
Yellow fever
Cholera
Japanese B Encephalitis

21

What is disease control? What diseases does this apply to?

Reducing incidence to a locally acceptable level:
- Diarrhoeal disease

22

What is disease elimination? What disease does this apply to?

Reduce incidence to zero in an area:
- Neonatal tetanus

23

What is infection elimination? What diseases does this apply to?

Reducing incidence of infection of a specific agent in an area:
- Measles
- Polio

24

What is erradication? What diseases does this apply to?

Permanent worldwide reduction of incidence to zero:
- Smallpox
- Rinderpest

25

What is extinction? What diseases does this apply to?

Agent no longer exists in nature or labs:
- None!

26

What can CYT009-GhrQb be used to treat? How does it work?

Obesity therapy
'Instructs' immune system to produce anti-ghrelin Ab response:
- Ghrelin is a peptide regulator of eating

27

What can the BCG vaccine be used to treat?

Bladder cancer:
- Approved intravesically
Eliminates white cells that destroy β-cells in pancreas:
- ?T1DM