immunology Flashcards

(60 cards)

1
Q

primary immune response

A

occurs the first time an immune system encounters, generates memory cells with high specificity, can take 14 days

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2
Q

secondary immune response

A

occurs following a previous encounter, more rapid, previously generated

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3
Q

five types of immunoglobulins

A

IgG, IgA, IgM, IgD, IgE

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4
Q

IgE

A

hypersensitivity (allergies and parasite), present in serum in lowest concentration of all Igs

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5
Q

IgD

A

unknown function, found in B cells

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6
Q

IgM

A

First Ig produced in immune response, most efficient complement fixing Ig. Pentamer

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7
Q

IgA

A

Major Ig. Dimer

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8
Q

types of vaccines

A

live attenuated, inactivated, subunit, toxoid

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9
Q

live attenuated

A

similar to natural infection, stored in cool place, can cause disease in weakened immune system.

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10
Q

inactivated

A

uses killed version of pathogen, may need boosters, will not weaken immune

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11
Q

subunit

A

uses dead pathogen in pieces, strong specific response, may need booster, fine for weak people

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12
Q

toxoid vaccines

A

uses a toxin made by the pathogen, tetanus, my require boosters, safe for weak.

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13
Q

infants

A

cannot produce antibodies until 3-6 months

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14
Q

innate

A

inborn, present at all times, responds immediately, responds uniform

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15
Q

acquired

A

6 days to respond, antigen specific, keeps memory

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16
Q

types of white blood cells

A

neutrophils, eosinophil, basophil

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17
Q

neutropenia

A

decrease in neutrophils can cause a severe infection

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18
Q

neutrophilia

A

increase in neutrophils, bacterial infection, drug intox, tissue necrosis.

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19
Q

neutrophil function

A

move to site of pathogen engulf it and destroy it. Adherence, migration, phagocytosis, bacterial killing

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20
Q

lymphocytes

A

includes b cell t cell and natural killer cells

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21
Q

t lymph function

A

cell mediated immunity

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22
Q

b lymph function

A

part of the humoral immunity can bind to antigen

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23
Q

natural killer cells function

A

kill infected cells

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24
Q

eosinophils function

A

reddish orange granules allergic disease, parasite infections, and chronic inflammation.

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25
basophils function
large dark purple mediators of the inflammatory response called mast cells
26
monocyte
large macrophages function phagocytosis
27
RBC should be
biconcave disc, 6-8 um, no inclusions, 4 heme groups, 4 globin chains
28
RBC membrane
semi perm for water and anions. no cations pass
29
hypoxia
tissues deprived of oxygen (EPO hormone)
30
hematopoiesis
the process of producing RBC, WBC, and platelets. Occurs in marrow
31
burr cells
could be sign of old blood
32
immature RBC
reticulocyte
33
sickle cell anemia
sickle cell
34
schistocyte
cells lysing
35
acanthocytes
irregular projections unlike burr
36
tear drop
spleen taken over
37
organ produces urine
kidney
38
reasons for urinalysis screening
disease diagnosis, progression of disease, monitor treatments
39
best for protein anal, microscopic anal, preg
first morning voided
40
three safety
gloves, gown, wash hands
41
things that go down with time urine
glucose, RBC/WBC, urobilinogen, casts, bilirubin, ketones, clarity, nitrites, trichomonas
42
things that go up with time urine
odor, pH, and bacteria
43
amber color
UTI
44
Red urine
hemo, food dye, beets
45
green urine
pseudomonas infection
46
blue urine
clorets, drugs
47
black urine
melsum, levodopa, homosetistic acid
48
turbidity
clarity- bacteria, semen, increased cells
49
foul ammonia urine
bacterial infection
50
sweet urine
diabetes
51
maple syrup urine
maple syrup urine disease
52
mousy urine
PKU
53
ph raised
vegatarian, vomiting, old sample
54
protein raised
kidney disorder, exercise, hypertension
55
glucose urine
diabetes
56
ketones urine
diabetic ketoacidosis
57
blood
kidney damage
58
bilirubin
hepatobiliary disease
59
leukocyte esterase
inflammation
60
urobilinogen
hemolysis of RBC