Immunology and Disorders

Question 1

Scleritis is what type of hypersensitivity reaction?

Answer 1

III

Question 2

OCP is what type of hypersensitivity reaction?

Answer 2

II

Question 3

Which type of reaction that activates complement?

Answer 3

II

Question 4

Which type of reaction occur when antigen-antibody complexes accumulate in tissue to attract leukocytes?

Answer 4

III

Question 5

PUK is what type of reaction?

Answer 5

III

Question 6

If Basophils or mast cells are seen on cytology what does it imply?

Answer 6

Vernal conjunctivitis

Question 7

Contact dermatoblepharitis has what type of reactions?

Answer 7

1. type I 2. Type IV

Question 8

Vernal KC is what type of reaction?

Answer 8

I and IV

Question 9

In VKC the (GIANT) papillary reaction occurs mostly where?

Answer 9

Upper palpebral conj

Question 10

Thickened gelatinous mounds with vascular injection is called what and see in what

Answer 10

Horner Trantus dots (macroaggregates of degeneated eosinophils and epithelial cells), VKC

Question 11

Shield ulcer occurs with what disease?

Answer 11

VKC - develop in the superior or central cornea.

Question 12

How does AKC (atopic) differ from VKC?

Answer 12

1. AKC have disease year-round. 2. AKC patients are older 3 AKC papillae are smaller and on both upper and lower 4. in AKC extensive Corneal vascularization and opacification secondary to chronic epithelial disease can occur.

Question 13

Ligneous conjunctivitis has been linked to what systemic deficiency?

Answer 13

Type I plasminogen.

Question 14

When does stromal keratitis from congenital syphillus develop?

Answer 14

Late in the first decade - or even later

Question 15

What are 5 nonocular signs of congential syphillus?

Answer 15

1. dental deformities 2. bone and cartilage abnl 3. CN VIII deafness 4. Rhagades (circumoral radiating scars) 5. MR

Question 16

What are the characteristics of acquired syphilic stromal keratitis?

Answer 16

typically U/L; uveitis and retinitis are much more common manifestations of acquired syphilis than keratitis.

Question 17

In Cogan Syndrome when does the URI occur?

Answer 17

1-2 weeks before the eye and ear symptoms.

Question 18

PUK happens usually with what systemic dx?

Answer 18

RA (also seen in Wegners, SLE, Polyarteritis noduosa, ulcerative colitis,)

Question 19

Which one is painful: PUK or Moorens?

Answer 19

Mooren’s

Question 20

Which one has scleral and corneal involvement PUK or Moorens?

Answer 20

PUK

Question 21

What kind of corneal movement does Mooren’s have?

Answer 21

Starts peripherally and spreads circumferentially and then centripetally with a leading undermined edge of de-epithelized tissue. A slower movement of ulceration proceeds toward the sclera.

Question 22

What systemic disease is associated with Mooren ulcer type PUK?

Answer 22

Hepatitis C

Question 23

Mooren’s dz is a/w with what systemic illness?

Answer 23

NONE.. by defintion it has no underlying systemic illness

Question 24

Neomycin causes what to the cornea and what type of immune reaction?

Answer 24

Peripheral corneal infiltratres; Wessely immune ring; TYPE 3 rxn

Question 25

How do you treat Stevens Johnson Syndrome?

Answer 25

1. Pulsed IV steriods

2. Amniotic membrane

Question 26

ANA is positive in which disorder most commonly?

Answer 26

SLE (RA is ANA -)

Question 27

What is the most common ocular finding of SJS?

Answer 27

Episcleritis

Question 28

What is the order of potency for topical prednisolone?

Answer 28

Pred acetate 1%> pred phosphate > loteprednol > FML