Immunology And Serology (HISTORY) Flashcards
(33 cards)
Who was able to demonstrate the 1st cross-immunity?
Edward Jenner
Edward Jenner’s work laid the foundation for immunology.
What disease does the variola major virus cause?
Smallpox
Variola major is a severe form of smallpox with high mortality rates.
What is the significance of the blood transfusion performed on Pope Innocent VIII?
It was one of the earliest recorded blood transfusions
This event highlights the historical attempts at blood transfusion before modern techniques were developed.
What did Braxton and Hicks recommend in 1869?
Sodium phosphate
This recommendation was related to medical treatments of that era.
What substance was introduced by Loutit and Molison in 1943?
ACD
Citrate is used as an anticoagulant in blood transfusions.
Who introduced the gel test in 1985?
Yves Lapierre
The gel test is used in serological testing.
What role did Dr. Charles Drew have in relation to blood banks?
Director of the American Red Cross blood bank
Dr. Drew was instrumental in developing blood storage and transfusion techniques.
What nickname was given to Mary Mallon due to her actions?
Typhoid Mary
She was a carrier of Salmonella typhi and unknowingly infected others.
Fill in the blank: Vaccinia causes _______.
Cowpox
Vaccinia is used in the smallpox vaccine.
What was introduced by Gibson in 1957?
CPD
Variolation:
Inhalation of pulverized small pox lesion crust.
Variola minor:
Alastrin
Mild small pox
In 1914, Hustin introduce _____.
Sodium Citrate
Marry Mallon:
Carrier of salmonella typhi
Who demonstrated that protection from smallpox could be generated by the transfer of pustular material from a cowpox lesion?
Edward Jenner
Edward Jenner’s work laid the foundation for vaccination.
What significant discovery did Louis Pasteur make?
Therapeutic vaccination
Pasteur’s work on vaccination was crucial in developing vaccines for various diseases.
What was the first report of a live (attenuated) vaccine for rabies?
Modified organism
This marked a significant advancement in the field of immunology.
Who demonstrated that cells could ingest foreign material, now classified as phagocytes?
Eue Merchnikov
This discovery was fundamental in understanding immune response.
What did Jules Bordet discover?
Complement
Bordet’s discovery contributed to the understanding of immune system functions.
Who discovered precipitins?
Robert Kauffman
This work was important for understanding antibody responses.
Who won the Nobel Prize for his work on antitoxins?
Emil Adolf von Behring
His research was pivotal in the development of serum therapy.
What discovery was awarded the Nobel Prize in 1978 regarding antibodies?
Genetic principles underlying the generation of antibodies with different specificities
This work was crucial for immunology and genetics.
Who demonstrated the structure of antibodies?
Gerald Edelman and Rodney Porter
Their work advanced the understanding of immunoglobulin structure.
What concept did Niels Jerne demonstrate?
Immunoregulation
Jerne’s work contributed to the understanding of how the immune system regulates itself.
