Immunology-Serology

Question 1

• Study of all aspects of the immune system in terms of structure and function

Answer 1

IMMUNOLOGY

Question 2

Immune system not responding to antigens?

Answer 2

Immunodeficiency

Question 3

• Immune system not recognizing self from non-self

* Example: lupus

Answer 3

Autoimmune Disease

Question 4

• Division of immunology that tries to detect and measure antigens and antibodies

Answer 4

SEROLOGY

Question 5

• Ability of an organism to resist a particular infection or toxic by the action of specific antibodies of sensitized (stimulated) WBC.

Answer 5

IMMUNITY

Question 6

Any substance that can stimulate an immune response?

Answer 6

Antigens (Immunogen)

Question 7

• Proteins made by plasma cells in response to an antigen

Answer 7

Antibodies (Immunoglobin)

Question 8

• IgM, IgG, IgA, IgD, IgE (GAMED)
• (mu, gamma, alpha, delta, epsilon)
• IgM - Increase if first exposure to antigen
• IgG - Most abundant antibody in the body; increase on the second or on further exposure to antigen; Only antibody that can cross the placenta
• IgA - secretion
• IgD - found in B-cell
• IgE - allergy

Answer 8

MEMORIZE

Question 9

Site of antigen where antibody binds

Answer 9

Epitopes

Question 10

1. Identify and quantifying:
   o Antigens
   o Antibodies
2. Investigate problems/disorders with the immune system, such as autoimmune diseases and immunodeficiency disorders
3. Determines organ, tissue and fluid compatibility for transplantation

Principles of Immunologic and Serologic Method
• Binding of antigen to a specific antibody
• Plays an important role in the diagnosis of diseases using different tests.

Immunoassays
• Designed to detect the presence of either antigen or antibody in the unknown sample.

Answer 10

break