Immunopathology Week 3 - Lecture 2

Question 1

What is Aplasia?

Answer 1

a. Lack of or faulty development of an organ or tissue or

b. A sudden cessation of growth, causing the tissue to shrink or even to
disappear. It is an acquired defect

Example: Aplasia of bone marrow.

Question 2

What is Hypoplasia?

Answer 2

Hypoplasia is the underdevelopment or incomplete development of
an organ or tissue.
Example: Turners Syndrome.

Question 3

What is Agenesis?

Answer 3

it generally refers to the situation
when absence of development of an
organ or tissue occurs during
embryonic development where there
is some abnormality with tissues.
Example: Organs such as Kidneys, ovaries and testes may fail to develop during embryological development.

Question 4

What is dystrophy?

Answer 4

This is abnormal growth and differentiation
of tissue usually due to genetic disorders of
nutrition and metabolism.

Example: Duchenne muscular dystrophy.

Question 5

What are Hamartomas?

Answer 5

Is a focal developmental anomaly,
characterised by an overgrowth of
normal cells in a nest in the tissue in
which they are usually found.
example: Mole

Question 6

What is Choristomas?

Answer 6

This is a focal overgrowth of normal cells
arising developmentally, found in a tissue
where these cells usually would not be
present.
Example: Endometriosis.