IMMUNOSERO Flashcards

(58 cards)

1
Q

area of biology that is concerned with process by which all living organisms defend themselves against infection

A

IMMUNOLOGY

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2
Q

recognize and defend itself against specific pathogens or antigens

A

IMMUNITY

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3
Q

2 general types of immunity

A
  1. Anatomical Barriers
  2. Humoral Barriers to Infection
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4
Q

first line of defense

A

Anatomical Barrier

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5
Q

Different factors of Anatomical Barriers;

A

Mechanical Factors
Chemical Factors
Biological Factors

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6
Q

From what factors of anatomical barrier are the Fatty acids and Surfacants

A

Chemical Factors

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7
Q

Normal flora of the skin and GIT

A

Biological Factors

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8
Q

Important role in INFLAMMATION

A

Humoral Factors

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9
Q

Found in the Serum or at the Site of Infection

A

Humoral Factors

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10
Q

Humoral Barrier to infection

A

Humoral Barriers

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11
Q

Part of Innate Immunity

A

Complement System

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12
Q

Act as chemotactic antigens for phagocytic cells

A

Coagulation System

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13
Q

Other Non-Specific Plasma Proteins

A

Lactoferrin and Transferrin
Interferons
Betalysin
Properdin

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14
Q

group of chemical messengers

A

Interleukins

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15
Q

TRUE OR FALSE.
Interleukins are also secreted by different cells to activate and stimulate the function of other cells

A

TRUE

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16
Q

third line of defense

A

acquired or adaptive immunity

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17
Q

cell responsible for the specific immune response

A

lymphocytes

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18
Q

matures in the bone marrow

A

B cells

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19
Q

matures in the thymus

A

T cells

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20
Q

types of specific immunologic reactions

A

Humoral Immunity
Active
Passive
Cellular

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21
Q

cell mediated

A

cellular immunity

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22
Q

result of transmission of antibodies

A

passive immunity

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23
Q

result of actual infection

A

active immunity

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24
Q

antibody mediated

A

Humoral immunity

25
antibodies that are found in ECF (extracellular fluid)
Blood Plasma Lymph Mucus
26
defense against bacteria, bacterial toxins and viruses that circulate freely in body fluids before they enter cells
Humoral immunity
27
exposure to antigen because of disease process
Naturally Acquired Active Immunity
28
through vaccination
Artificially Acquired Active Immunity
29
Natural antibodies ; Antibodies pass from mother to fetus via placenta
Naturally Acquired Passive Immunity
30
Injection of Antibodies ; Immunity is short-lived
Artificially Acquired Passive Immunity
31
defense against intracellular organisms
Cellular Immunity
32
Two major lineages
Myeloid Precursor Lymphoid Precursor
33
Maturation sites of Immune system organs
Primary
34
Central organ where all immune cells are born
Bone marrow
35
T cells Maturation
Thymus
36
Activation sites of Immune System Organs
Secondary
37
Two types of immune system organs
Primary Secondary
38
Secrete antibody ; Humoral Immunity
B Cells
39
T cells subsets and cytokines ; Cellular Immunity
T cells
40
Binds directly to antigens for which they are specific
B cells
41
recognize and bind to antigenic peptide when they come in contact with APCs (antigen presenting cells)
T cells
42
Examples of APCs
Macrophages Dendritic cells
43
Largest tissue of the body
Bone marrow
44
Bone marrow total weight
1,300-1500 g in ADULT
45
Main source of the hematopoietic stem cells of the blood cell lines
Bone Marrow
46
where T,B and NK cells arise from
Common Lymphoid Precursor (CLP)
47
Small, flat, bilobed organ found on the thorax
Thymus
48
Average weight at: Birth= ___ Puberty= ____
Birth= 30 g Puberty= 35 g
49
Where the activation of lymphocytes occurs ; Strictly dependent on antigenic stimulation
Secondary Lymphoid Organs
50
Largest secondary lymphoid organ approx. 12cm and weighing 150g in adult
Spleen
51
Located in the upper left quadrant of the abdomen
Spleen
52
Makes up >1/2 of the total volume; function is to destroy old rbcs
Red pulp
53
Approx 20% of the total wt of spleen and contains the lymphoid tissue
White pulp
54
located along lymphatic ducts and serve as central collecting points for lymph fluid from adjacent tissues
Lymph nodes
55
found in the gastrointestinal, respiratory, and urogenital tracts
MALT
56
found in the mucous membrane lining of the oral and pharyngeal cavities
Tonsils
57
Potential site for contact with foreign antigens
Appendix
58
Most of these are T cells, which are uniquely positioned to combat any antigens that enter through the skin
CALT