Immunosuppression Flashcards
Increasing numbers of organ transplants
Disease might lead to decreased immunity
Increased number of patients on immune supppresants
Explosion in medical therapy needed for these patients
Immunodeficient definition
Any state where immune system is below optimum level
Immunosuppression definition
Art of artificially depressing the immune system
Immunocompromised definition
Those at risk due to reduced immune function
What are the two types of immune system?
What do they both do?
What are the main cells in both?
Congenital immunodeficiency
Acquired immunodeficiency
MORE COMMON THAN CONGENITAL IMMUNODEFICIENCY
What can we give to cause immunosuppression
Immunosuppression - organ transplant
Steroids
steroids can cause immunosuppression
Steroids
Side effects of steroids
Cushing syndrome
Infection
Delayed healing
Osteoporosis
Addisonian crisis
Addisonian crisis
Steroid cover in dentistry?
Do NOT need to give steroid cover for routine dentistry
Oral side effects of immunosuppression
Specific
Cyclosporine
Tacrolimus
Both of the above are immunosuppressant drugs and both cause GINGIVAL HYPERPLASIA because of increased collagen synthesis and decreased collagen breakdown
Treated by:
Surgical reduction
Improved OH
Modification of drug treatment
Screening questions
Summary
SEE SUMMARY PAGE
