Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathology > Immunotherapies 3 > Flashcards

Immunotherapies 3 Flashcards

1
Q

Which age depletes lymphocyte and modulates T cell activation and migration?

A

Anti-thymocyte globulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the Mechanism of action of daclizumab?

A

IL2 receptor antibody

Targets CD25 cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which anti-CDIIa agent inhibits T cell migration?

A

Efalizumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the mechanism of action of Alemtuzumab

A

Monoclonal antibody that depletes lymphocytes by binding to CD52

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which agent causes the side effect of CMV infection?

A

Alemtuzumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the indications for Alemtuzumab?

A

CLL

MS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Name 4 anti-TNFalpha agents

A

Infliximab
Adalimumab
Certolizumab
Golimumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the 5 indications for infliximab?

A 
Rheumatoid arthritis
Ankylosing spondylitis
Psoriasis
Psoriatic arthritis
Inflammatory bowel disease
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the mechanism of action of etanercept?

A

TNAalpha/beta receptor p75 IgG fusion protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the 4 indications for etanercept

A

Rheumatoid arthritis
Ankylosing spondylitis
Psoriasis
Psoriatic arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the mechanism of action of Ustekinumab

A

Anti-IL12 and IL23 by binding to p40 subunit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What agent is indicated in ankylosing spondylitis and is an anti-IL17A agent

A

Secukinumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

which agent can cause a vascular necrosis of the jaw as a side effect

A

Denosumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the mechanism of action of denosumab

A

anti-RANK ligand, inhibits RANK mediated osteoclast differentiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the indications for denosumab

A

Osteoporosis
Multiple Myeloma
Bone Mets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is the mechanism of action of infliximab?

A

Anti-TNFalpha agent

Pathology (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions