Imort Flashcards

(49 cards)

1
Q

What is the change in cardiac parameters during inspiration?

A

↑ RV preload, ↓ LV preload

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2
Q

What murmurs increase during inspiration?

A

Most right-sided murmurs (↑ RV blood volume)

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3
Q

What murmurs decrease during inspiration?

A

Most left-sided murmurs (↓ LV blood volume)

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4
Q

What is the change in cardiac parameters during Valsalva strain phase?

A

↓ RV & LV preload

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5
Q

What murmurs increase during Valsalva strain phase?

A

MVP & HCM (↓ LV blood volume)

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6
Q

What murmurs decrease during Valsalva strain phase?

A

Most valvular murmurs (↓ flow through valve)

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7
Q

What is the change in cardiac parameters during abrupt standing?

A

↓ RV & LV preload

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8
Q

What murmurs increase during abrupt standing?

A

MVP & HCM (↓ LV blood volume)

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9
Q

What murmurs decrease during abrupt standing?

A

Most valvular murmurs (↓ flow through valve)

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10
Q

What is the change in cardiac parameters during squatting?

A

↑ RV & LV preload, ↑ LV afterload

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11
Q

What murmurs increase during squatting?

A

Most valvular murmurs (↑ flow through valve)

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12
Q

What murmurs decrease during squatting?

A

MVP & HCM (↑ LV blood volume)

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13
Q

What is the change in cardiac parameters during passive leg raise?

A

↑ RV & LV preload

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14
Q

What murmurs increase during passive leg raise?

A

Most valvular murmurs (↑ flow through valve)

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15
Q

What murmurs decrease during passive leg raise?

A

MVP & HCM (↑ LV blood volume)

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16
Q

What is the change in cardiac parameters during hand grip?

A

↑ LV afterload

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17
Q

What murmurs increase during hand grip?

A

AR, MR & VSD (↑ aortic & LV pressure)

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18
Q

What murmurs decrease during hand grip?

A

AS (↓ transvalvular pressure gradient)

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19
Q

What is the protein defect in Familial Chylomicronemia Syndrome (Type I)?

A

Lipoprotein lipase, ApoC-2

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20
Q

What are the elevated lipoproteins in Familial Chylomicronemia Syndrome (Type I)?

21
Q

What are the major manifestations of Familial Chylomicronemia Syndrome (Type I)?

A

Acute pancreatitis, Lipemia retinalis, Eruptive xanthomas

22
Q

What is the protein defect in Familial Hypercholesterolemia (Type II A)?

A

LDL receptor, ApoB-100

23
Q

What are the elevated lipoproteins in Familial Hypercholesterolemia (Type II A)?

24
Q

What are the major manifestations of Familial Hypercholesterolemia (Type II A)?”

A

Premature atherosclerosis, Tendon xanthomas, Xanthelasmas

25
What is the protein defect in Familial Dysbetalipoproteinemia (Type III)?
ApoE
26
What are the elevated lipoproteins in Familial Dysbetalipoproteinemia (Type III)?
Chylomicron & VLDL remnants
27
What are the major manifestations of Familial Dysbetalipoproteinemia (Type III)?"
Premature atherosclerosis, Tuboeruptive & palmar xanthomas
28
What is the protein defect in Familial Hypertriglyceridemia (Type IV)?
Polygenic
29
What are the elevated lipoproteins in Familial Hypertriglyceridemia (Type IV)?
VLDL
30
What are the major manifestations of Familial Hypertriglyceridemia (Type IV)?"
Associated with coronary disease, pancreatitis & diabetes
31
Watery Diarrhea in HIV
Cryptosporidium
32
Bad news should be delivered?
honestly, directly, and using small pieces of information at a time
33
A test result for rheumatoid factor is positive. How about Complement (C3) Segmented Neutrophils Interleukin-1 (IL-1) Tumor Necrosis
Complement (C3): Decreased Segmented Neutrophils: Increased Interleukin-1 (IL-1): Increased Tumor Necrosis Factor (TNF): Increased Glucose: slightly decreased
34
Thoracic Duct Anatomy
near the left subclavian vein and the aorta
35
Peptide transporter (TAP) gene
Bare lymphocyte
36
First Aortic Arch
Part of maxillary arteries (branches of the external carotid arteries)
37
Second Aortic Arch
Stapedial arteries (which regress) and hyoid arteries
38
Third Aortic Arch
Common carotid arteries +Proximal part of the internal carotid arteries
39
Fourth Aortic Arch
Left: Part of the arch of the aorta. Right: Proximal part of the right subclavian artery
40
Fifth Aortic Arch
This arch either completely regresses
41
Sixth Aortic Arch
Left: - Proximal part: Left pulmonary artery - Distal part: Ductus arteriosus (which becomes the ligamentum arteriosum after birth) Right: - Proximal part: Right pulmonary artery - Distal part: Regresses
42
Relative Risk (RR)
RR = (a/(a+b)) / (c/(c+d)). P1/P2
43
Absolute Risk Reduction (ARR)
ARR = (c/(c+d)) - (a/(a+b)). P2-P1
44
Relative Risk Reduction (RRR)
RRR = ARR / (c/(c+d)) or RRR = 1 - RR
45
Number Needed to Harm (NNH)
NNH = 1 / AR
46
Number Needed to Treat (NNT)
NNT = 1 / ARR
47
Attributable Risk (AR)
AR = (a/(a+b)) - (c/(c+d))
48
SE
SD/. \/ñ
49
CI of mean
Mean +_ z * SE Z 68%= 1 Z 95%=2 Z 99%= 2.5