Important Clinical and Historical Features of some diseases Flashcards
(150 cards)
Wickham’s striae, bilateral symmetrical distribution of lesions with female predilection. Saw tooth retepegs. liquefaction degeneration of basal layet, colloid or civatte bodies.
Lichen planus
Auspitz’s sign, painless non pruritic papules
No involvement of oral mucosa and Monro’s abscesses.
Psoriasis
Psoriasis, Reiter’s syndrome. benign migratory glossitis and ectopic geographic tongue.
Psoriasis form lesions
Positive Nikolsky’s sign. Tzanck cells and granular immuno Ruorescence.
Pemphigus
Nikolsky’s sign+ve Dilapidated brick wall effect.
Familial benign chronic pemphigus (Mailey-Hailey disease)
Butterfly distribution of lesions . Carpet tack extensions .LE.cell phenomenon Lupus erythematosus speckled or particulate immuno fourescence.
Lupus erythematosus
.Lesions on skin are rare except on genitalia
Ocularinvolvement is the most serious complication
Cicatrial pemphigoid/ Benign mucous membrane pemphigoid / Ocular pemphigus
Gingival tissues are involved
Separation of the basement membrane with the connective tissue from the overlying epithelium.
Bullous pemphigoid / Parapemphigus
Target or Iris or Bulls Eye Lesions Erythema multiforme Recent H/0 of Herpes simplex infection
Erythema multiforme
Corps ronds and grains, Leafing out pattern of parabasal cells Defect in demosome tonofilament complex.
Keratosis follicularis(Darriers disease)
Hyperkeratosis, acanthosis with a deep groove filled with parakeratin and absence of granular layer constituting the Cornoid Lamella
Porokeratosis of Mibelli
Mask like face, claw like hands, Raynauds phenomenon, CREST syndrome. staff board like tongue, coup de sabre and generalized widening of the periodontal ligament
scleroderma
Hyper elasticity of skin, hyper extensibility of joints. defective heating, rubber man
Lack of normal scalloping of DEJ
Ehlers danlos syndrome
Ulcers occurring on the masticatory mucosa, common in children Prodromal symptoms are present Presence of Lipschutz bodies and Ballooning degeneration
Primary herpetic stomatitis
Koplik spots.
Measles (Rubeola)
Bilateral contagious parotitis, elevated serum amylase level.
Mumps
Herpetic labialis, Herpetic whitlow (painful herpes simplex vrirus infection of a finger from direct inoculation. Most common in physicians, dentists, and nurses as a result of exposure to the virus in patient’s mouth) Ulcers on the masticatory mucosa, Tzanck cells.
Recurrent or secondary herpes virus infection
Ulcers occurring on the labile mucosa Precipitated commonly in stress. No history of Prodromal symptoms
Recurrent Apthous stomatitis
Sore throat, ulcers on the faucial pillars, soft and hard palate, Occurs as an epidemic summer Caused by Coxsackie group A virus
Herpangina
UNTLATERAL painful vesicles along the course of sensory nerves Tzanck cells
Herpes Zoster
Fungal disease affecting the reticulo-endothetial system and resembles granulomatous infection.
Phycomycosis (mucormycosis)
Strawberry tongue, Raspberry tongue.
Scarlet fever
Lock Jaw due to muscle trismus Risus sardonicus (Rigidity of facial muscles) Risus opisthotonus (Rigidity of entire body muscles)
Tetanus
Hebra nose
Rhinoscleroma