Important genes

Question 1

what does SOD1 stand for

Answer 1

superoxidate dimutase

Question 2

what chromosome is SOD1 on?

Answer 2

21

Question 3

what is the action of superoxide dimutase

Answer 3

an enzyme that breaks down superoxide (free radical)

Question 4

what disease is SOD1 assoc with?

Answer 4

ALS

Question 5

what is ApoE gene short for?

Answer 5

Apolipoprotein E

Question 6

what chromosome is ApoE gene on?

Answer 6

19

Question 7

what does ApoE gene do?

Answer 7

codes for apolipotpoteins if not working can lead to deposits in the brain

Question 8

what disease is ApoE assoc with?

Answer 8

Alzhemiers

Question 9

what does PS stand for?

Answer 9

Presenilin

Question 10

where is PS1

Answer 10

chrome 14

Question 11

where is PS2

Answer 11

chrome 1

Question 12

what do PS1 & PS2 do

Answer 12

code for proteins that build enzymes to cleave other proteins

Question 13

what disease is PS1 & PS2 in

Answer 13

Alzheimers

Question 14

what chromosome is the insulin gene on?

Answer 14

11

Question 15

what does the insulin mean do?

Answer 15

codes for protein that is responsible for the fx & devision of beta cells (DM1)

Question 16

what chromosome MHC gene on?

Answer 16

6

Question 17

what does MHC gene do?

Answer 17

Essential for acquired immune system to recognize foreign molecules

Question 18

when is MHC important?

Answer 18

disfunction of immune system - autoimmunity gives PREDISPOSITION

Question 19

where is the glucokinase gene

Answer 19

7

Question 20

what does glucokinase gene do

Answer 20

enzyme that facilitates phosphorylation so that glucose stay in cell once it enters

Question 21

when is glucokinase gene?

Answer 21

MODY