Important Info Random/maybe 2.2 Flashcards

1
Q

Which of the following has side effect of hair growth?

A

Minoxidil

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2
Q

Which of the following blocks ETA action and decreases formation of IP3?

A

Bosentan

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3
Q

Which statin has the least drug-drug interaction

A

Pravastatin

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4
Q

Atorvastatin has what mechanism of action

A

Inhibits HMG-CoA reductase

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5
Q

What inhibits 2 steps before statin?

A

Bempedoic acid

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6
Q

Which of the following factor Xa inhibitors

A

All of the above (apixaban, edoxaban, fondaparinux)

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7
Q

Which of the following inhibits factor Xa AND thrombin?

A

Heparin

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8
Q

Which of the following has an ADR that causes skin reactions due to injection of drug?

A

Alirocumab

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9
Q

Which drug has blurry vision as an ADR?

A

fibrates

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10
Q

Pulmonary hypertension due to lung disease is which group?

A

Group III

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11
Q

Retavase has what mechanism of action?

A

Convert plasminogen to plasmin

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12
Q

Thromboxane A2 has a role in which step platelet plug

A

Activation

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13
Q

Spironolactone inhibits which molecule?

A

Aldosterone

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14
Q

Which of the following is an ADR of ace inhibitor due to bradykinin buildup?

A

cough

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15
Q

Which of the following drugs cause hyperkalemia?

A

All of the above

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16
Q

Which drug decreases intracellular calcium release from blocking IP3?

A

hydralazine

17
Q

Which of the following can be taken through inhalation?

A

Both B and C (treprostinil and iloprost)

18
Q

Which of the following anticoagulant medications is taken via IV?

19
Q

Rovastatin has what ADR?

A

Both A and C (hepatotoxicity and myopathy)

20
Q

44 year old man smokes and has diabetes. How many risk factors for ASCVD?

21
Q

Which of the following is positive pleotropic effects for statins?

A

All of the above (plaque stabilization, improved endothelial function, reduced platelet aggregability)

22
Q

What is the term for stopping bleeding from an injured blood vessel?

A

Hemostasis

23
Q

What is in Virchow’s triad?

A

All of the above (stasis, vessel wall injury, hyperstability)

24
Q

Which of the following is a vitamin K dependent clotting factor

A

II and VII (but question was wrong and didn’t have both as an answer)

25
Which drug has taste disturbance as an ADR?
Warfarin
26
What is the coagulation parameter to monitor warfarin?
INR
27
Which drugs cause bleeding?
Both B and C (Aspirin and ticaglor) ??
28
What prevents conversion of ang 1 to ang II
Lisinopril (not aliskirin)
29
Which one has a pregnancy contraindication?
Statin
30
Which of the following drugs causes angioedema?
-pril (ace inhibitor)
31
How does candesartan inhibit vasoconstriction?
AT1 receptor
32
Which intracellular molecule has to deal with vascular smooth muscle tone?
Calcium
33
Selexipag has what mechanism of action?
Selective prostacyclin IP receptor agonist
34
Which of the following has the least amount of triglycerides?
HDL
35
Which one is bad cholesterol?
LDL
36
What is the mechanism of action of Ezetimibe?
Blocks transport protein NPC1L1 at brush border of enterocyte
37
Which drug blocks the formation of Protein C and protein S?
Warfarin
38
Which of the following is antifibrinolytic?
Aminocaproic acid and tranemaic acid (NOT atlepase)