Important take aways

Question 1

rim- priming and docking of synapses and recruits calcium channels and stp via calcium and dag binding domains
-pdz binds to elks and calcium channels
-c2 domains bind to unc13

-rimbp - binds to rim and calcium channels

-munc13-synaptic vesicle priming and snare proteins for vesicle fusion - stp via priming activity and positions synapses within the active zone

-liprin-alpha - interacts with transsynaptic cell adhesion moleucles and rim and elks ptps and lar

-elks - number of synaptic vesicles at actuve zone and anchors and positions calcium channels