Important Terminologies Flashcards
The process by which a drug enters the bloodstream after administration.
Absorption
The fraction of an administered dose that reaches the systemic circulation and is available for distribution to the site of action.
Bioavailability
The interaction between a drug and a target molecule, such as a receptor or enzyme.
Binding
The rate at which a drug is eliminated from the body.
Clearance
The movement of a drug from the bloodstream to the tissues and organs.
Distribution
The movement of a drug from the bloodstream to the tissues and organs.
Distribution
The process by which a drug is removed from the body, including metabolism and excretion.
Elimination
The inhibition of an enzyme’s activity by a drug, which can affect its metabolic pathways.
Enzyme inhibition
The state in which the rate of absorption equals the rate of elimination, resulting in a constant plasma concentration.
Equilibrium
The time it takes for the concentration of a drug in the body to decrease by half due to elimination.
Half-life
The study of the rates and mechanisms of drug absorption, distribution, metabolism, and elimination.
Kinetics
The breakdown of a drug into its metabolites, which can be active or inactive.
Metabolism
The study of the effects of drugs on the body, including their mechanisms of action and response.
Pharmacodynamics
The study of how genetic variations affect an individual’s response to drugs.
Pharmacogenetics
Is the study of how drugs move through the body.
It encompasses the processes of absorption, distribution, metabolism, and excretion (ADME).
Pharmacokinetics
It encompasses the processes of absorption, distribution, metabolism, and excretion (ADME).
A specialized target macromolecule that binds a drug and mediates its pharmacological action.
Receptor
The pharmacodynamics (PD) response to the drug, which is all the effects of the drug on any physiologic and pathologic process, in relation to effectiveness and adverse reactions.
Response
The way by which a drug, fluid, poison, or other substance is taken into the body.
Routes of administration
