Increased Red Cell Destruction Determine Mechanism

Question 1

HS

Answer 1

Rec cell membrane disorder

Question 2

Hereditary Elliptocytosis

Answer 2

Red cell membrane disorders

Question 3

2 enzyme deficiencies in in inherited genetic disorders

Answer 3

Hexose monophosphatr shunt enzyme deficiencies

Glycolytic enzyme deficiencies

Question 4

G6PD

Answer 4

Hexose monophosphatr shunt enzyme deficiencies

Question 5

Glutathione synthetase deficiency

Answer 5

Hexose monophosphatr shunt enzyme deficiencies

Question 6

Pyruvate kinase deficiency

Answer 6

Glycolytic enzyme deficiency

Question 7

Hexokinase deficiency

Answer 7

Glycolytic enzyme deficiency

Question 8

Hemoglobin abnormalities mechanisms

Answer 8

Deficient globin synthesis

Structurally abnormal globins

Question 9

Thalassemia

Answer 9

Deficient globin synthesis

Question 10

Sickle cell disease

Answer 10

Structurally abnormal globins

Question 11

Unstable hemoglobins

Answer 11

Structurally abnormal globins

Question 12

Acquired genetic defects mechanisms

Answer 12

Deficiency of phophatidylinositol-linked glycoproteins

Antibidy-mediated destruction

Question 13

PNH

Answer 13

Deficiency of phsphatidylinositol-linked glycoproteins

Question 14

Hemolytic disease of the new born (Rh disease)

Answer 14

Antibody-mediated destruction

Question 15

Transfusion reactions

Answer 15

Antibody-mediated destruction

Question 16

Drug induced

Answer 16

Antibody-mediated destruction

Question 17

Autoimmune disorders

Answer 17

Antibody-mediated destruction

Question 18

Mechanical trauma mechanisms in hemolysis

Answer 18

Mucroangiopathi. Hemolytic anemias
Cardiac traumatic hemolysis
Repetitive physical trauma
Infections of red cells
Toxic or chemical injury
Membrane lipid abnormalities
Sequestration

Question 19

Hemolytic uremic syndrome

Answer 19

Microangiopathic hemolytic anemias

Question 20

DIC

Answer 20

Microangiopathic hemolytic anemias

Question 21

Thrombotic thrombocytopenia purpura

Answer 21

Microangiopathic hemolytic anemias

Question 22

Defective cardiac valves

Answer 22

Cardiac traumatic hemolysis

Question 23

Bongo drumming

Answer 23

Repititive physical trauma

Question 24

Marathon running

Answer 24

Repititive physical trauma

Question 25

Karate chopping

Answer 25

Repititive physical trauma

Question 26

Malaria

Answer 26

Infections of red cells

Question 27

Babesiosid

Answer 27

Infections of red cells

Question 28

Clostridial sepsis

Answer 28

Toxic or chemical injury

Question 29

Snake venom

Answer 29

Toxic or chemical injury

Question 30

Lead poisoning

Answer 30

Toxic or chemical injury

Question 31

Abetalipoproteinemia

Answer 31

Membrane abnormalities

Question 32

Severe hepatocellular liver disease

Answer 32

Membrane abnormalities

Question 33

Hypersplenism

Answer 33

Sequestration