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Unit 1 Pharm III > Indications > Flashcards

Indications Flashcards

1
Q

Local anesthetic largely limited to dentistry

A

Prilocaine (amide)

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2
Q

At clinical doses, vasoconstricts.

Use: Peripheral and epidural blocks

A

Ropivacaine

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3
Q

Opioid good for longer surgeries because of its cardiovascular profile

A

Fentanyl

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4
Q

Use: ADHD (stimulant)

A

Amphetamines

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5
Q

Would also work for methanol poisoning by competing for metabolism

A

Ethanol

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6
Q

Use: Autism

A

Buspirone

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7
Q

Opioid which is a cough suppressant at much lower doses than analgesia

A

Codeine

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8
Q

Use: narcolepsy

A

Amphetamines

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9
Q

DOC Methanol poisoning that inhibits alcohol dehydrogenase

A

Fomepizole

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10
Q

May slow progression of the Alzheimer’s and delay transition from mild cognitive impairment to AD

A

Cholinesterase inhibitors

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11
Q

Short acting barbiturate for induction of anesthesia

A

Thiopental

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12
Q

DOC: refractory to lithium bipolar

A

Valproic acid

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13
Q

First line drug psychosis

A

Risperidone

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14
Q

Long acting barbiturate for prevention of seizures

A

Phenobarbital

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15
Q

Increases L dopa levels in the periphery so lower levels of l dopa can be used

A

Carbidopa

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16
Q

Use: reduce dental bleeding

A

Cocaine (ester)

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17
Q

DOC opioid overdose

A

Naloxone

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18
Q

Treatment if seizures occur during alcohol withdrawal

A

Lorazepam

Phenytoin (secondary)

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19
Q

Uses:

  1. absence and general tonic-clonic seizures
  2. bipolar disorder
  3. Migraine prophylaxis
A

Valproic acid

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20
Q

Benzo for acute muscle spams and pain from an injury

A

Diazepam

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21
Q

Reversal of benzodiazepines in respiratory depression

A

Flumazenil

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22
Q

Opioid for short surgical procedures with midazolam

A

Fentanyl

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23
Q

Only effective for parkinson’s for 3-4 years and does not affect progression

A

L-dopa

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24
Q

Resets sleep wake cycle, promotes sleepiness without GABA effect

A

Ramelteon

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25
Q

DOC social anxiety

A

Paroxetine

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26
Q

Use: decrease cravings in alcoholism (antidepressant)

A

Bupropion

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27
Q

Early/mild parkinsons

A

Amantadine

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28
Q

Relieves anxiety without producing sedation

A

Buspirone

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29
Q

Use: refractory complex partial seizures

A

Vigabatrin

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30
Q

Use: ADHD+Anxiety

A

Buspirone

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31
Q

Drug of last choice for psychosis due to agranulocytosis

A

Clozapine

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32
Q

IV benzo for short surgical procedures to produce anterograde amnesia

A

Midazolam

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33
Q

Use: migraine prevention

A

Topiramate

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34
Q

Depression associated with bipolar disorder

A

Lurasidone (atypical antipsychotic)

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35
Q

Hypersomnia drug

A

Flumazenil

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36
Q

Dopamine system stabilizer for psychosis

A

Aripiprazole

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37
Q

Good for sleep aid and pain management, but not a good antidepressant and not good for males (priapism)

A

Trazodone

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38
Q

Form of phenytoin that can be injected IM for status epilepticus

A

Fosphenytoin

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39
Q

Maintenance treatment of opioid addiction, partial mu agonist

A

Buprenorphine

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40
Q

Opioid receptor antagonist also used to block reward pathway in alcoholics

A

Naltrexone

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41
Q

Antidepressant for chronic pain from TMJ or fibromyalgia

A

TCAs

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42
Q

DOC depression

A

SSRIs, specifically Citalopram

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43
Q

Mu agonist

A

Meperidine

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44
Q

Stronger than morphine

A

Hydromorphine

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45
Q

GABA independent anxiolytics

A

Ramelteon

Buspirone

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46
Q

Use: neuropathic pain

A

Gabapentin

Pregabalin

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47
Q

Refractory bipolar disorder in combination with lithium

A

Carbamazepine

48
Q

Use: PMS

A

Buspirone

49
Q

Topical anesthetic of upper respiratory tract mucous membraine

A

Cocaine (ester)

50
Q

Use this opioid for patients with renal dysfunction because the metabolites don’t accumulate

A

Hydromorphine

51
Q

Regulation of sleep wake cycle, promotes wakefullness

A

Suvorexant

52
Q

Use: Trigeminal neuralgia

A

Carbamazepine

53
Q

DOC partial seizures

A

Carbamazepine

54
Q

Uses:
Tourette’s
Acute mania

A

Ziprasidone

55
Q

Uses: fibromyalgia, post-op pain

A

Pregabalin

56
Q

Also used for neuropathic pain and post-menopausal hot flashes

A

SNRIs

57
Q

Use: diagnostic nerve blocks

A

Procaine (ester)

58
Q

Anticonvulsant that can be used for anxiety

A

Pregabalin

59
Q

If your opioid addict is a healthcare professional….

A

Naltrexone

60
Q

DOC absence seizures

A

Ethosuximide

61
Q

DOC for enuresis

A

TCAs

62
Q

Meperidine is weird because

A

Metabolite normeperidine accumulates→ seizures→ DO not use >48 hours, high doses, or renal failure

Anticholinergic→ tachycardia, pupil dilation (opposite of most opioids)

63
Q

Anticonvulsant used to decrease craving in recovering alcoholics

A

Topiramate

64
Q

Sleeping pills

A

Z drugs

65
Q

DOC epidural anesthesia

A

Lidocaine (amide)

66
Q

Topical only local anesthetic, OTC

A

Benzocaine

67
Q

3 anticonvulsants for bipolar disorder

A

Carbamazepine
Lamotrigine
Gabapentin (off label)

68
Q

Sedation for pediatric dental procedures

A

Choral Hydrate

69
Q

Use: infiltration anesthesia

A

Procaine (ester)

70
Q

Adjunct for partial and generalized tonic-clonic seizures

A

Gabapentin

71
Q

Rescue of off periods in patients on L-dopa, temporary, must be injected

A

Apomorphine

dopamine receptor agonist

72
Q

Partial mu agonists that could precipitate withdrawal if given to chronic opioid users

A

Pentazocine

Buprenorphine

73
Q

Can be used in Bulimia and Alcoholism

A

SSRIs

74
Q

DOC retrobulbar ophthalmic local anesthesia

A

Tetracaine (ester)

75
Q

Antipsychotic to promote sleep onset and maintenance

A

Quetiapine

76
Q

1st non-stimulant treatment for ADHD

A

Atomoxetine

77
Q

Inverse differential block→ causes motor block before or without sensory block

A

Etidocaine

78
Q

DOC depression in the elderly

A

Sertraline

79
Q

Control muscle spasms form stroke or neuro injury

A

Botulinum toxin

80
Q

Parkinson’s drugs that continue to be effective even as disease progresses, used in combination with L-dopa

A

Dopamine receptor agonists

81
Q

Depression which hasn’t responded to other drugs

A

MAOIs

82
Q

Modest antiparkinson, improve rigidity and tremor but NOT bradykinesia

A

Anticholinergics

83
Q

Not water soluble and must be injected IV for status epilepticus

A

Phenytoin

84
Q

DOC for psychosis

A

Atypical antipsychotic

85
Q

DOC acute psychosis

(ER setting, drug induced)

A

Haloperidol

86
Q

Combined with 10% dextrose to make it hyperbaric for spinal anesthesia

A

Tetracaine (ester)

87
Q

DOC restless leg syndrome

A

Ropinirole

88
Q

Uses:

  1. post-op analgesia
  2. Spinal and epidural anesthesia
  3. infiltration blocks
A

Bupivacaine (amide)

89
Q

Use: Infantile spasm (West’s syndrome)

A

Vigabatrin

90
Q

Maintenance treatment of opioid addicts

A

Methadone

91
Q

Decreases craving of alcohol by restoring disturbed GABA/glutamate balance to normal

A

Acamprosate (GABA analogue)

92
Q

DOC for status epilepticus

A

Diazepam

Lorazepam

93
Q

Z drug with a long half life so it is used for long term treatment of insomnia

A

Eszopiclone

94
Q

Benzodiazepines for insomnia

A

Flurazepam

Temazepam

95
Q

Local anesthetic that’s also an antiarrhythmic

A

Lidocaine (amide)

96
Q

Opioid which is a cough suppressant with no analgesia

A

Dextromethorphan

97
Q

Use: ADHD (antidepressant)

A

Bupropion

98
Q

DOC peripheral blocks

A

Mepivacaine (amide)

99
Q

Less preferred MAOI due to serious side effects

A

Phenelzine

100
Q

DOC infiltration blocks

A

Lidocaine (amide)

101
Q

Opioids used to treat diarrhea (2)

A

Loperamide

diphenoxylate/atropine

102
Q

Dangerous drug that will give you a bad hangover with alcohol

A

Disulfiram

not recommended

103
Q

Prevention of seizures during alcohol withdrawal

A

Diazepam

Chlordiazepoxide

104
Q

Opioid with long term control of pain/ hard to treat pain

A

Methadone

105
Q

combination of l-dopa/ carbidopa/ entacapone

A

Stalevo

106
Q

Opioid with less respiratory depression because its a partial mu agonist

A

Pentazocine

107
Q

Adjunct for partial seizures

A

Tiagabine

108
Q

DOC OCD

A

Paroxetine

109
Q

Improves positive and negative psychosis symptoms and can be used for bipolar

A

Olanzapine

110
Q

Benzo with alternate uses:

  1. Absence seizures
  2. Myoclonic seizures
  3. Infantile spasms (West syndrome)
A

Clonazepam

111
Q

Depressed patient with insomnia and anxiety

A

Mitrazapine

112
Q

Use: quitting smoking (antidepressant)

A

Bupropion (Zyban extended release)

113
Q

Rapid cycling manic/depressive episodes

A

Valproic acid

114
Q

Amide + ester group local anesthetic

A

Articaine

Decreased half life due to additional metabolism
Dental use

115
Q

Treatment of neuroleptic malignant syndrome

A

Dantrolene

116
Q

May inhibit progression of parkinson’s by decreasing free radicals produced during dopamine metabolism

A

MOA-B inhibitors

Unit 1 Pharm III (4 decks)

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