Induction Drugs Flashcards by Joanna Brown

Q

PROPOFOL

INDUCTION DOSE

A

1.5 - 2.5 MG/KG

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Q

PROPOFOL

ONSET

A

30-60 SECONDS

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Q

PROPOFOL

DURATION

A

5-10 MINUTES

THIS IS NOT THE HALF-LIFE!

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Q

PROPOFOL

METABOLISM

A

LIVER AND LUNGS

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Q

PROPOFOL

INFUSION DOSE

A

25-200 MCG/KG/MIN

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Q

KETAMINE

INDUCTION DOSE

A

IV: 1 - 2 MG/KG

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Q

KETAMINE

ONSET

A

IV: 30 SECONDS

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Q

KETAMINE

DURATION

A

10 - 20 MIN

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Q

KETAMINE

METABOLISM

A

LIVER P450

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Q

ETOMIDATE

INDUCTION DOSE

A

0.2 - 0.4 MG/KG IV

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Q

ETOMIDATE

ONSET

A

30-60 SECONDS

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Q

ETOMIDATE

DURATION

A

5 - 15 MIN

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Q

ETOMIDATE

METABOLISM

A

LIVER P450 AND PLASMA ESTERASES

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Q

DEXMEDETOMIDINE

LOADING DOSE AND INFUSION RATE

A

LOADING: 1 MCG/KG OVER 10 MIN

INFUSION: 0.4-0.7 MCG/KG/HR

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Q

DEXMEDETOMIDINE

ONSET

A

10 - 20 MIN

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Q

DEXMEDETOMIDINE

DURATION

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A

10 - 30 MIN AFTER INFUSION STOPS

Q

DEXMEDETOMIDINE

METABOLISM

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A

LIVER P450

Q

MIDAZOLAM

INDUCTION DOSE

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A

0.1 - 0.4 MG/KG

Q

MIDAZOLAM

ANXIOLYSIS

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A

0.01 - 0.1 MG/KG

Q

MIDAZOLAM

ONSET

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A

30-60 SECONDS

Q

MIDAZOLAM

DURATION

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A

20 - 60 MINUTES

Q

MIDAZOLAM

METABOLISM

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A

LIVER P450 AND INTESTINAL P450

Q

FENTANYL

STAND ALONE INDUCTION DOSE

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A

1.5-5 MCG/KG

Q

FENTANYL

CONCOMITANT ADMINISTRATION INDUCTION DOSE

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A

WITH PROPOFOL: 50-100 MCG IV

WITH ETOMIDATE: 1-5 MCG/KG (LOW) OR 20-40 MCG/KG (MEDIUM)

**Glycopyrrolate** Reversal Dose

0.2 mg per 1mg Neostigmine

**Neostigmine** Reversal Dose

4 Twitches: 0.04 mcg/kg 2 - 3 Twitches: 0.08 mcg/kg

**Sugammadex** 2 Twitches

2 mg/kg

**Sugammadex** 0 Twitches, 1-2 post tetanic

4 mg/kg

**Sugammadex** Post RSI Dose

16 mg/kg