Infant Disorders Flashcards

(34 cards)

1
Q

CL occurs in

A

1 in 700 births

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2
Q

CL is a str or fx prob

A

str

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3
Q

What problem occurs embryonically in CL? When does this occur?

A

maxillary and nasal sinuses do not fuse

Week 5-8 gestation

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4
Q

CL: uni or bilateral?

A

Either

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5
Q

What teratogens play a role in CL? Examples of positive/negative?

A

Positive: smoking, viral infections
Negative: folic acid deficiency

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6
Q

Why does CL usually occur w CP?

A

The teratogen present in week 5-8 for CL usually has not gone away by week 9-12 for CP

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7
Q

How often does CP occur?

A

1 in 2000

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8
Q

Brief description of CP

A

congenital, incomplete fusion of palatine structures at week 9-12

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9
Q

What is the strongest Et factor in CP?

A

smoking during pregnancy

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10
Q

How often does pyloric stenosis occur?

A

1 in 1000

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11
Q

Is pyloric stenosis congenital/genetic?

A

No

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12
Q

Is pyloric stenosis a structural or functional problem?

A

functional

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13
Q

Why is there constriction of the pyloric spinster in pyloric stenosis?

A

Hypertophy

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14
Q

Et of pyloric stenosis

A

hypergastrinemia, PGE, erythromycin exposure

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15
Q

PGE is…

A

a local hormone

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16
Q

When does pyloric stenosis occur?

A

2-8 weeks of AGE

17
Q

How does obstruction occur in pyloric stenosis

A

hypertrophy of sphincter = constriction = inflammation/exudate formation = obstruction

18
Q

manifestation of PS?

A

projectile vomiting

19
Q

What are 2 complications of PS?

A

dehydration, malnourishment

20
Q

Diagnostic confirmation of PS?

A

URQ palpation = mass felt

21
Q

How do we treat PS?

A

sx to debulk muscle

22
Q

What kind of problem is gastroesophageal reflux?

A

functional and neuro prob

23
Q

How often does gastroesophageal reflux occur in infants? When does it subside?

A

50%. After 3 months

24
Q

Et of gastroesophageal reflux?

A

neuromuscular

25
Why do growth problems occur in gastroesophageal reflux?
pain during feeding, so baby doesn't want to feed
26
tx for gastroesophageal reflux?
H2RA, antacids, PPI, modify feeding (positioning, smaller feeds, thickened), fundoplication
27
Et of Hirschsprung Disease?
RET gene on Chr 10 = codes for proteins involved in cell signalling, helps in formation of neural tissue in colon
28
Patho of Hirschsprung Disease
areas of colon lack PS ganglia = no peristalsis in that area = accumulation of contents = colon distension = abdominal distention
29
How do we treat Hirschsprung Disease
sx removal of aganglionic segment
30
How often does intussusception occur?
1 in 4000
31
What happens in intussusception?
Intestines invaginate into adjoining valve
32
What adjoining valve do intestines usually invaginate into in intussusception?
Ileocecal valve
33
Why does this invagination occur?
Region of smaller diameter is pushed into one with a larger diameter due to pressure build up
34
How do we treat intussusception?
hydrostatic reduction