infant feeding Flashcards

(81 cards)

1
Q

trend in breastfeeding rates up to 6mths in UK

A

marked drop off despite WHO recommendation of exclusive BF for 6mths and then alongside complimentary feeds for up to 2yrs

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2
Q

constituents of human milk

A
cytokines
IL-7
enzymes
milk lipids
oligosaccharides
lactoferrin
leukocytes
immunoglobulins
stem cells
lymphocytes
growth factors
vits and minerals
fats 
carbohydrates
proteins
water
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3
Q

formula milk constituents

A
vits and minerals
fats 
carbohydrates
protein 
water
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4
Q

main difference between breast milk and formula

A

basic nutritional consituents vary

breastmilk contains many more live constituents that promote health

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5
Q

breast milk vs formula - water

A

water used to make formual can easily become contaminated - climate issues, over use of cleaning products or fluorine

breast milk doesn’t have this issue

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6
Q

breast milk vs formula - protein

A

breast milk - more whey based (60-80%) and easier to digest, main protein (alpha lactalbumin, make up >20% of total protein) has been associated with the destruction of over 40 types of cancer cells

formula - cows milk protein, associated with increased risk of baby developing juvenile onset diabetes

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7
Q

breast milk vs formula - carbohydrates

A

breast milk - lactose is 1y carb, provides ~40% of total calories

formula - lactose is also more prevalent in UK formula; may also see sucrose, fructose and glucose in soya/lactose free formula

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8
Q

breast milk vs formula - fats

A

breast milk - long chain polyuns. FAs support the development of the entire NS (incl. retinol development - improved eyesight)

formula - fats change depending on the market; currently they are mainly vegetable (rapeseed oil, sunflower oil, coconut oil, algal oil), some contain egg or fish oil

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9
Q

why are fats required in infants

A

essential for brain development and absorption of fat soluble vitamins, and are a major calorie source

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10
Q

breast milk vs formula - vitamins and minerals

A

formula - extra vits and minerals and added to the powder to ensure they are sustained for the entire shelf life so amounts vary

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11
Q

why are vitamins and minerals important

A

healing wounds
supporting bone growth
immune system
etc

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12
Q

examples of growth factors present in breast milk

A

epidermal, insulin and transforming factors which promote gut growth

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13
Q

when is epidermal GF higher

A

mothers who have preterm babies

linked to a reduction in necrotising enterocolitis (NEC) and other inflammatory repsonses

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14
Q

what role do growth factors play in early life

A

role in early life programming

may be associated with a reduced risk of obesity and cancer in later life

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15
Q

what is the role of transfer factors

A

enable effective absorption of nutrients in the milk e.g. lactoferrin

also help with absorption of fats and vitamins

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16
Q

role of lactoferrin

A

assists with absorption of iron - reduces amount of free iron which attracts batceria

also bactericidal - kills E coli

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17
Q

what is the role of stem cells in breast milk

A

have the ability to develop into many different cell types

evidence that these cells remain in the system long after BF has stopped

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18
Q

immunoglobulins in breast milk

A

IgA, IgG, IgM, IgD
IgA - provides protective coating to baby’s gut - prevents entry of pathogenic bacteria and enteroviruses (E. Coli, salmonella, streptococci, staph, pnuemococci, rotavirus etc) - protects against gastroenteritis, resp infections etc

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19
Q

role of leukocytes in breast milk

A

destroy harmful bacteria

macrophages - produces lysozyme which disrupts bacterial cell wall

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20
Q

oligosaccharides in breast milk

A

> 200 types of simple carbs in breast milk

influence the development of the microflora by increasing number of beneficial bacteria in baby’s gut - protects baby against infections e.g. otitis media, resp, urine, GI

encourage some cells in the gut to produce an adhesive protein substance which helps seal the gaps between cells in the gut wall - prevents harmful bacteria and allergens from crossing into the baby’s system

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21
Q

milk lipids in breast milk

A

damage outer surface of certain virus types

reduce infection rate in baby

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22
Q

enzymes in breast milk

A

aid digestion and absorption

some destroy bacteria

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23
Q

IL-7 in breast milk

A

linked to the size of the thymus - breast fed babies have much larger thymus than formula fed babies - stronger immune system

also has a role in stimulating antibody producing cells

plays a part in reducing risk of childhood leukaemia

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24
Q

cytokines in breast milk

A

important constituent in boosting immune system

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25
special features of colostrum
``` protective factors concentrated nutrition strong anti-inflamamtory factors stimulates gut growth - helps cells and villi proliferate small volumes - intentional laxative effect ```
26
what is the role of the laxative effect of colostrum
to clear meconium | helps minimise jaundice
27
what is the difference between colostrum and mature breast milk
colostrum is smaller volumes and more concentrated new born babies would find the XS water in mature breast milk difficult to process (immature kidneys) healthy term babies don't become dehydrated - surfeit of interstitial fluid they need to process in the first few days
28
not breastfeeding increases the risk of what in babies
``` gastroenteritis resp infections allergies - mixed evidence obesity T1 and 2 DM SIDS NEC ``` exclusive BF gives best protection but some is greater than none
29
not breastfeeding increases the risk of what in mothers
breast cancer ovarian cancer hip fractures heart disease
30
when do babies begin to pick up their microbiome
may recieve exposure to maternal microbes in the womb lactobacilli more prevalent in the vagina during pregnancy (friendly bacteria) as they pass through the vagina at birth vaginal birth, skin to skin and breast feeding through the mother's milk in the postnatal period and beyond
31
what is the role of our gut biome
generate our energy needs produce enzymes to digest food manufacture vitamines B, K and nicotinic acid regulate fat storage manufacture amino acids help w/ iron absorption create our individual immune system and help immune cells reproduce train our immune system on what is safe and what to reject
32
benefits of the first breast feed on gut health
live constituents in the milk develop the process of setting up the microbiome w/ high levels of bifidobacteria and oligosaccharides
33
results of insufficient bifidobacteria in the gut
children with insufficient bifidobacteria in their gut in the first year of life have an increased risk of obesity in later life.
34
what is especially important if a child is born by C sectioin
miss out on vaginal transfer of microbes | prolonged skin to skin contact and breast feeding
35
epigenetics and breastfeeding
breastfeeding may result in epigenetic changes which impact on: brain development baby's immune system baby's metabolic system
36
what is epigenetics
additional info that may be layered on top of the sequence of molecules that make up our DNA epigenome attaches to and modifies the original gene
37
epigenetics and generational change
changes to our genes can be passed down to future generations via maternal line e.g. famine in the netherlands - effect could be seen 3 gens later childhood abuse has been shown to affect DNA patterns - link between victims and ill health in adulthood
38
when is our DNA most receptive to epigenetic changes
in utero - 3yrs alters the way our organs and our predisposition to certain diseases develop
39
what impacts the infant's epigenome
maternal environment during pregnancy | infant's first recieved nutrition
40
breastmilk and leptin
breastmilk has the ability to turn on/off certain epigenetic changes e.g. gene for leptin appetite is influenced by breastmilk babies who are breastfed have higher levels of leptin at 1mth of age formula milk may dampen leptin production and is associated with higher levels of obesity
41
updating the baby's immune system at each feed
broncho-mammary pathway: pathogens inhaled entero-mammary pathway: pathogens ingested antibodies produced and sent to breasts antibodies incorporated into breast milk
42
how does the mother affect the baby's immune system
mother's body works to monitor her environment and produce antibodies to current infections that she detects in her lungs/gut antibodies are passed directly to the breastmilk so baby is provided with protection with as little delay as possible mother and baby need to be together for this to work
43
how can we protect breastfeeding
international code of marketing of breastmilk substitutes - the code UK law - hasn't yet fully implemented the code professional accountability
44
what is 'the code' with regards to marketing formula milk
prohibits all promotion of bottle feeding and sets out requirements for labelling and information on infant feeding. Any activity which undermines breastfeeding also violates the aim and spirit of the Code. The Code is not an anti-bottle feeding measure. It is as keen to make sure bottle feeding is done as safely as possible as it is to ensure the protection and promotion of breastfeeding.
45
the code states that companies must not...
promote their products in hospitals, shops or to the general public give free samples to mothers or free/subsidised supplies to hospitals or maternity wards give gifts to health workers or mothers promote their products to health workers: any information provided by companies must contain only scientific and factual content promote foods or drinks for babies give misleading information have direct contact with mothers.
46
UK law regarding formula milk
intended to ‘regulate labelling and restrict advertising and presentation of infant and follow-on formula so as not to discourage breastfeeding.’ not as robust as the Code and companies are able to find ways around the law. One of the biggest weaknesses is that, while the Code considers follow-on formula (i.e. milk intended for babies over six months) to be a breastmilk substitute, the UK law does not. This allows the companies to promote their brand name and logos via advertising of follow-on milks.
47
conflict of interest re. formula milk
Sponsored study days / smaller education sessions / meetings offered for staff or parents on public service premises Staff attending sponsored study days Individual staff engaging with the companies e.g. by speaking at sponsored events, writing articles, blogs etc. for the companies Awards and other gifts being made to individual staff by the companies or by a separate organisation which is being sponsored by the companies.
48
what parents using formula need to know
``` 1st milks for 1st yr - no need for follow on all brands are similar information on prep and sterilising cow's milk from 1yr responsive bottle feeding ```
49
what is responsive bottle feeding
baby is held close and feeds are paced | important to reduce overfeeding and obesity
50
what are the 3 stages of lactation
lactogenesis 1 - breast development and colostrum production from ~16wks gestation 2 - onset of copious milk secretion occurring between 32 and 96hrs after birth 3 - maintenance of milk production
51
what does lactogenesis 1 involve
differentiation of alveolar epithelial cells into lactocytes that secrete colostrum from ~3-4mths of pregnancy
52
what causes lactogenesis 2
occurs in response to risk in prolactin and a decrease in pregnancy hormones milk will come in regardless of whether a woman wants to breastfeed or not
53
external changes to the breast during pregnancy - Montgomery's tubercles
appear on the areola to secrete an antiseptic sebum to lubricate the area sebum also creates a scent to entice the baby to begin to search in the area for their first feed
54
changes in hormones after birth
oestrogen and progesterone levels drop prolactin and oxytocin levels rise in response to touch, smell and sight of baby baby begins spontaneous breast seeking behaviour mothering behaviours initiated
55
prolactin-receptor theory
the more early, frequent surges of prolactin there are, the greater the number of receptor sites that become primes max number of receptor sites = max numbers of functioning lactocytes from that point onwards, max triggering of the mothering response
56
prolactin - role, responsive to, levels highest, long term production
responsible for milk production responsive to touch and stimulation levels higher at night frequent contact/feeds sets up for long term production
57
oxytocin - role, levels highest, what can delay 'let down'
responsible for milk delivery acts on muscle cells in pulsatile action levels higher when baby is near stress can temporarily delay 'let down'
58
rise and fall in prolactin levels
increase the most in the immediate postpartum period rise and fall in proprotion to the frequency, intensity and duration of nipple stimulation concentration in the blood doubles in response to suckling and peaks ~45mins after the beginning of a breastfeeding session levels fall ~50% in the first week after birth in breasfeeding women if women don't breastfeed, levels reach non-pregnant levels by 7 days postpartum
59
oxytocin release
levels will remain high as long as baby is kept close and milk will start to be release in response to early feeding of behaviour clues if baby is away from mum these early clues might be missed, if mum can only respond when her baby is crying and distressed her own cortisol levels will be raised and compete w/ oxytocin
60
prolactin and oxytocin - mum and baby bonding
prolactin and oxytocin work together to help a new mother feel calm yet protective of her baby oxytocin helps form a bond between mother and baby
61
feedback inhibitor of lactation (FIL)
Circulating prolactin within bloodstream controls milk production especially in the early weeks post birth. Volumes can be irregular at first so mothers may experience full breasts and leaking as the supply and demand establishes itself. As breasts become very full either through ineffective milk removal or long spacing of feeds a whey protein in the milk called FIL slows down synthesis by signalling to the cells to stop production. In addition it is believed that the down regulation (reduced milk production) is also caused by pressure within the full breast flattening and expanding the cells and the receptor sites, making it difficult for prolactin to attach to and enter the cells.
62
oxytocin - the love hormone
``` works on feeling and emotions lowers BP and improves sleep reduces stress levels by 'taking on' cortisol reduces pain sensitivity boosts immune system ```
63
skin to skin contact - baby friendly standard
all mothers have skin to skin contact w/ baby after birth at least until after the first feed and for as long as they wish all mothers are encouraged to offer the first feed in skin contact when the baby shows signs of readiness to feed mothers and babies who are unable to have skin contact immediately after birth are encouraged to commence skin contact as soon as they are able
64
why should skin contact be prolonged
triggers lactation and mothering hormones regulates temp, HR and breathing in baby colonises baby w/ microbes from mother, father and their environment stimulates feeding behaviour reduces stress hormones in mother and baby
65
why is skin to skin still important in bottle fed babies
triggers mothering hormones regulates temp, HR and breathing in baby colonises baby w/ microbes - esp important if not recieving breastmilk reduces stress hormones in mother and baby starts mother-baby bond
66
9 stages baby goes through after birth
``` birth cry relaxation awakening activity rest crawling familiarisation suckling sleeping ```
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stage 1 - birth cry
after birth | distinctive cry familiar to midwives as baby expands his lungs
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stage 2 - relaxation
after birth cry no mouth movement hands and body totally relaxed
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stage 3 - awakening
2-4 mins after birth small thrusting movements of head and body eyes beginning to open some shoulder movement
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stage 4 - activity
4-12 mins after birth | stable open eyes, rooting, salivating, hand to mouth, hand to breast to mouth, tongue protrusion
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stage 5 - rest
frequent after birth | lots of rest periods after activity
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stage 6 - crawling
18-54 mins after birth crawling, sliding, leaping and drawing up knees to push forward lots of rooting searching
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stage 7 - familiarisation
29-62 mins after birth VERY important stage - can last 20 mins or more licking nipple, touching, massaging breast begins to interact with mum and dad stimulating mum's hormones
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stage 8 - suckling
49-90 mins | self attaches after working out best approach and begins to feed
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stage 9 - sleeping
90-120 mins
76
catecholamine levels in baby after birth
raised after birth - help support transition to extra uterine life these decrease when baby begins to feel safe in a known environment as levels drop baby begins to display activity and becomes more awake and interested in their environment
77
what is the role of the rest periods during the instinctive search
enables baby to consolidate and integrate what they have already experienced all to do with imprinting and shouldn't be rushed
78
what is the role of the crawling stage
helps baby move closer to the breast | massages mother's uterus, helping it to contract - important for oxytocin release but also helps prevent PPH
79
what is the role of familiarisation
baby approaches mother's breast, spends time imprinting and working out how best to approach and attach for feeding if rushed by staff (putting baby onto the breast) this can result in baby struggling to attach at subsequent feeds - biggest reason many mothers stop breastfeeding in the early weeks
80
separation and stress
term baby separated for 6 hrs has increased stress pre-term baby receiving high-tech care has greatly increased stress one hour of skin contact can reduce stress hormone levels by 75%
81
what can skin contact help with
attachment challenges - overhelped, pain and discomfort boosting milk supply unsettled babies and mothers breast refusal postnatal depression or low mood - oxytocin and prolactin and released which are both mood boosters, baby will also feel nurtured and safe just because it feels good - mums and dads