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Flashcards in Infection 101 Deck (11):
1

what type of cell wall has lipoteichoic acid?

 

what about LPS?

 

what are the porins in the second plasma membrane important for drug delivery?

see image

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2

Tell me the big bad bugs on CSF Gram stain

 

GP cocci

CP bacilli

 

G neg cocci

G neg bacilli

This is important for treatment of meningitis

 

1. Gram pos cocci is steph pneumoniae

 

2. Gram pos bacilli is Listeria

 

Gram neg cocci is neisseria 

 

Gram neg bacilli is H. influ

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3

what is a problem with the legionella urinary antigen?

this is a problem because it only detects the L. pneumophilia 1,

 

the MO legionella longbeacheae is also common in QLD

4

what does galactomannan test for?

 

what about beta-D-glucan?

the first one is assoc with aspergillus

 

the second is other fungal, but not cryptococcus

5

 which stages of syphilis are associated with positive serology, and which with negative?

primary syphilis (painless ulcer) is often sero neg

 

secondary and tertiary are usually sero pos

6

what is the most common pathogen with acute IE

 

what are some other causes of acute IE?

s. aureus is the main pathogen

 

s. pyogenes also important

7

what are the common pathogens associated with a subacute presentation of IE?

Strep viridans is a big deal

 

Enterococci

 

HACEK bugs

(Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, Kingella)

8

what are the risks of IE when the following come up as pos blood cultures?

 

1. s. mutans

2. s bovis 

3. s gallolyticus

4. s. gallolyticus pasteurianus

5. e. faecalis

6. s pyogenes

1. s. mutans is extremely likely to be IE. 14:1 (14 IE cases for each non-IE)

2. s. bovis biotype 1 = 6:1

also very strongly associated with colon CA/adenoma

3. s. gallolyticus is the new name for s bovis (see above

4. s. gallolyticus pasteurianus is 1:1

- strongly assoc with CRC

 

5. e. faecalis = 1:1

6. s. pyogenes is 1:32! (much more likely to be from skin)

9

what is the most common pathogen in IE in IVDU

 

what is the most common in prosthetic valve IE?

in IVDU, number 1, 2 and 3 are s. aureus

 

in prosthetic valve:

1. coag- neg staph

2. s. aureus

3. streptococci

4. gram-negs

10

what are the more common causes of culture negative endocarditis?

see pic

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11