Infection Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Investigations for infectious mononucleosis

A

Monospot test for heterophile antibodies
+ve = confirm
-ve = repeat in 5-7d (Ab can take 6w to appear)

FBC = lymphocytosis (+ atypical lymphocytes)

LFTs = ALT and AST 2-3x normal

EBV antibodies
IgM = rise early (acute infection)
IgG = suggest immunity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Management of infectious mononucleosis

A

Usually self-limiting (2-3w)

Avoid alcohol + contact sports

Steroids to relieve symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What drug to avoid in infectious mononucleosis

A

Amoxicillin

- can cause maculopapular rash and lead to allergy misdiagnosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what type of bacteria is c. diff

A

gram +ve rod

produces toxins A and B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Investigation of ? C.diff

A

FBC = raised WCC (correlates with severity)

Stool sample

  • toxin = infection
  • antigen = indicates exposure rather than infection
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tx of C. diff (first infection)

A

Oral vancomycin for 10 days

fidaxomicin 2nd line

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tx of severe C. diff

A

PO vancomycin + IV metronidazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Tx of recurrent C. diff

A

PO fidaxomicin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

treatment of influenza in at risk groups

A

PO oseltamivir
or
Inhaled zanamivir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Treatment of whooping cough

A

clarithryomycin or azithromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Ix for malaria

A

Thick and thin bloods film (repeat up to 3x in 48h if negative but clinical suspicion)

Rapid diagnostic tests (use antibodies to test for antigens)

Metabolic acidosis on ABG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Treatment of complicated falciparum malaria

A

1st line = artesunate
2nd line = quinine (cardiotoxic)

Follow up therapy = riamet (combination of artesunate and quinine) OR doxycylince/clindamycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Treatment of uncomplicated falciparum malaria

A

Riamet or malarone (ACT - artemisin based combination therapies)
Quinine (2nd line)

NO FOLLOW UP TX NEEDED

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Treatment of non-falciparum malaria

A

Chloroquinine or ACT

Follow up = primaquine (to prevent relapse)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly