Infection Flashcards

(32 cards)

1
Q

meningitis most common pathogen and empirical treatment? (for different age groups)

A
  • 0-2 months (Group B streptococcus, E.Coli) : benzylpenicillin + cefotaxime
  • >2months (N. Meningitidis, HiB, S pneumoniae) : ceftriaxone or cefotaxime, vancomycin if Gram positive
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2
Q

meningitis prophylaxis?

A

children, pregnant : Ceftriaxone

other adults : ciprofoxacin or rifampin

(rifampin contraindicated in severe liver disease, alcoholism)

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3
Q

a child with itching scalp, patchy loss of hair, scaling.

Dx and Tx?

A

Dx : Tinea capitis

Tx : PO antifungals (griseofulvin or terbinafine)

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4
Q

spontaneous baterial peritonitis

Dx, most common pathogen and Tx ?

A

ascitic fluid PMN > 250uL,

confirmed by culture

most commonly E.coli and other gut bacterial

initial Tx cefotaxime 2g IV 8 hourly

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5
Q

measles

how many days of school exclusion?

A

4 days from the onset of the rash

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6
Q

Tetanus vaccine schedule

A
  • DTPa 5 doses : 2, 4, 6 and 18 months, and 4 yrs old.
  • dTPa (reduced antigen) booster :
    • at 11-13 yrs
    • > 50 yrs old if last dose was more than 10 yrs ago
    • >65 yrs old if last dose was more than 10 yrs ago
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7
Q

an adult never been vaccinated against tetanus in the past. what to give?

A
  • dT 3 doses with 4 weeks intervals (1st dose should be dTPa. all three can be dTPa)
  • booster (dT or dTPa at 10 and 20 yrs after the primary doses)
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8
Q

18 months

high fever for 3 days

fever suddley subsides and maculopapular rash on trunk

no rash on face or limb

Dx?

A

roseola infantum

caused by HHV-6 or 7

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9
Q

severe endometritis?

what pathogens to cover?

which Abx?

what if she has a history of anaphylaxis to penicillin?

A

gonorrhea, chlamydia

ceftriaxone, azithromycin + metronidazole.

gentamicin, azithromycin + metronidazole

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10
Q

adult community acquired pneumonia.

empirical Abx?

A

Is it mild, moderate,severe?

  • Confusion : new onset
  • O pO2 <60mm or O2 sat <90
  • RR >30
  • BP sys <90 or diast < 60

none: mild, 1 : moderate, 2 or more: severe

mild :

  • amoxicillin 1g PO 8 hourly,
  • review in 48 hours.
  • (if cannot review in 48 hours, consider using doxycycline instead)
  • imporved –> 5 days,
  • slow improvement, 7 days.

moderate : admission

  • benzylpenicillin + doxycycline OR clarithromycin

Severe : ICU

  • benzylpenicillin +gentamicine + clarithromycin
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11
Q

the most common cause of gastroenteritis in adults and older children in australia?

in young children?

A

adults and older children : norovirus

youger children : rotavirus

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12
Q

thumb sign on lateral neck xray

Dx

m/c pathogen

Tx

A
  • epiglotittis
  • Past : H influenzae type B (not anymore due to the vaccine)
  • Current : Group A beta hemolytic streptoccocus
  • don’t delay airway protection because od Xray
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13
Q
A
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14
Q

cellulitis Abx?

A

IV flucoloxacillin

difloxacillin

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15
Q

hepatic hydatid cyst

which pathogen?

hosts?

how to eradicate?

human treatment?

A
  • pathogen : echinococcus
  • main host : dogs. intermediate host : sheep. accodental host : humans
  • eradication? :vaccination of lambs, deworming of dogs
  • Percutaneous drainage with albendazole therapy
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16
Q

exposure to measles.

Management?

1) Hx of vaccination (+)
2) vaccination history unsure
3) pregnant, immunecompromised, not sure of vaccination

A

1) Hx of vaccination (+) : reassure
2) vaccination history unsure : MMR vaccine now and 4 weeks later
3) pregnant, immunecompromised, not sure of vaccination : natural human immunoglobulin (NHIG)

17
Q

three strategies to reduce perinatal HIV transmission?

A
  1. use of zidobudine for the mom and baby
  2. elective C-sec
  3. no breastfeeding
18
Q

prophylactic antibiotics for HIV patients with low CD4 count?

what species to cover?

A

need to cover,

  • < 200: toxoplasmosis
  • < 100 : Pneumocystis jiroveci
  • < 50 : MAC

use

  • trimethoprim-sulfamethoxazole : for toxo and PCJ
  • azithromycin : for MAC
19
Q

diabetic foot ulcer anti?

A

mild infection : PO amoxicillin-clavulanate

deep or widespread infections, osteomyelitis : piperacillin-tazobactam, ticarcillin-clavulanate, meropenem, ertapenem, carbapenem,

moxi or ciprofloxacin + metronidazole

3rd cephalosporin + metronidazole

20
Q

a man travelled to Thailand recently

presented with

fever, joint pain, retro-orbital pain, rash all over body,

no LAP,

leukopenia, thrombocytopenia. elevated AST

21
Q

diffuse patchy infiltrates on x ray

suspected atypical pneumonia

What is the most common pathgen in each age group?

children < 2 yrs

school aged children

A

children < 2 yrs : viral pneumonia

school aged children : mycoplasma pneumoniae

22
Q

scabies Tx

A

permethrin 5% cream

23
Q

adult, recurrent sinusitis, failed with amoxacillin, trimethoprim/sulphamethoxazole.

Tx?

A

a fluoroquinolone 14-21 days

24
Q

roundworm infection Tx?

(Ascarid lumbricoid infection)

25
the most common pathogen for hospiral-acquired pneumonia
S. aureus P. aeruginosa
26
child with suspected pneumonia. Tx?
out patient : amoxacillin 3-5 days inpatient, not severe : amoxacillin. (if unable to take orally, consider benzylpenicillin IV) inpatient, sever (ICU) : ceftriaxone + azithromycin
27
Malaria prophylaxis with... ? in Thai/Myanmar/Cambodia in Central America in South America or Africa
Thai/Myanmar/Cambodia : doxycycline, atovaquone-proguanil Central America : chloroquine (chloroquine worsens psoriasis) South America or Africa : Mefloquine (mefloquine can cause panic attacks, paranoia)
28
vaccines that contain egg proteins?
Influenza yellow fever Q fever
29
typhoid or paratyphoid fevers (enteric fevers) salmonella from India Tx?
azithromycin or ceftriaxone India use ciprofloxacin only if stool culture or blood cultures confirm the sensitivity.
30
Rheumatic fever the revised Jones criteria
* 2 Major * 1 major + 2 minor + recent confirmed GAS infection (anti streprolysyn Ab, rapid antigen test for strep A , throuat culture) Major 1. carditis 2. polyarthritis 3. chorea 4. erythema marginatum 5. subcutaneous nodules Minor Clinical arthralgia fever laboratory elevated ESR/CRP 1st degree AV block
31
the most common pathogen for pneumonia in patients with cystic fibrosis under 5 years old ? 10 years and older?
* under 5 years old : S. aureus * 10 years and older : Pseudomonas aeruginosa
32
sore throat. when to give antibiotics?
streptococcal score * no cough * fever \> 38 * cervical LN * tonsillar exudates * age 3-14 0-1: supportive care 2-3 : culture, or RADT--\> Abx if positive \>4 : treat with amoxicillin