Infection and Response Flashcards

1
Q

What are pathogens

A

Microorganisms that enter the body and cause disease

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2
Q

How do bacteria make you feel ill

A

Secreting toxins

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3
Q

How do viruses make you feel ill

A

Reproduce inside of your cells
Mass copy themselves
Burst the cell releasing the copies

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4
Q

How do protists make you feel ill

A

Transmitted through vectors into/ onto your cells

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5
Q

How do fungi make you feel ill

A

Spores which are absorbed by the body

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5
Q

Examples of ways pathogens can spread

A

Water
Air
Direct Contact

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6
Q

What is measles

A

A virus

Spread by droplets from a person’s sneeze/cough
It can be very serious, causing rashes and sometimes inflammation of the brain

Most people are vaccinated against it as a child

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7
Q

What is HIV

A

A virus

Spread by sexual contact or sharing of blood. It causes flu-like symptoms for a few weeks and during this time it can be controlled with drugs

The virus attacks the immune cells

It lowers the body’s ability to cope with other pathogens

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8
Q

What is tobacco mosaic virus (TMV)

A

A virus that affects plants

It causes a mosaic pattern on the plant that discolours parts of the leaves

Therefore the plant’s ability to carry out photosynthesis is affected, stunting growth

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9
Q

What is rose black spot

A

A fungus

Causes purple/black spots to develop on the leaves of rose plants

The leaves can then turn yellow and then drop off

Less photosynthesis can happen then

It spreads through wind/water

Treated using fungicides or stripping affected leaves

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10
Q

What is malaria

A

A protist transported by a mosquito

It can cause repeating episodes of fever and the spread can be stopped by stopping mosquitos from breeding

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11
Q

What is salmonella

A

bacteria that causes food poisoning

the infected can suffer from fever, stomach cramps, vomiting and diarrhoea

you get it by eating food contaminated with the bacteria

in the UK most poultry is vaccinated

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12
Q

what is gonorrhoea

A

a STI caused by bacteria

caused by sexual contact

originally treated with an antibiotic by trickier now due to resistance

treated using antibiotics and barrier methods of contraception

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13
Q

how can the spread of disease be reduced/prevented

A

being hygienic
destroying vectors
isolating infected individuals
vaccination

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14
Q

Examples of your body’s defence system (not white blood cells)

A

skin as a barrier to pathogens

hair and mucus in nose trap particles that could contain pathogens

cilia which trap and waft mucus to the back of your throat

stomach produces HCl which can kill pathogens

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15
Q

What can phagocytes do

A

engulf and destroy pathogens - called phagocytosis

16
Q

What can lymphocytes do

A

Produce antibodies that are specific to the antigen

Produce anti-toxins to the bacteria

17
Q

How do vaccines work

A

Inject with a dead or inactive pathogen so that the body produces the antibodies that are specific to that virus and then if the body is infected again it will respond quicker

18
Q

pros and cons of vaccines

A

pros:
help to control some diseases
herd immunity

cons:
don’t always work
side affects

19
Q

what are painkillers and how are they different to antibiotics

A

drugs that reduce the symptoms

this is different to antibiotics which kill the bacteria

antibiotics don’t work on viruses!

20
Q

how can bacteria mutate to become resistant

A

the non-resistant bacteria die and the resistant ones continue to live and multiply

eventually all the bacteria will be resistant

21
Q

How to slow down the rate of development of resistant bacteria

A

not over-prescribe bacteria
finish course

22
Q

what is aspirin and where did it originally come from

A

painkiller and found in willow

23
Q

where did digitalis come from and what is it

A

used to treat heart conditions and found in foxgloves

24
how was penicillin discovered and by whom
alexander fleming one of his petri dishes containing bacteria and had mould on it but a section of it did not the mould was secreting a chemical (penicillin) that was killing the bacteria
25
stages of testing drugs
Preclinical drug trials - Tested on cells in labs and on computer programs - used to test side effects Animal trials - Tested on animals and monitoring them - can be used to figure out dose and side effects Human clinical trials - tested on healthy volunteers to see side effects Then tested on those suffering from the illness Then placebo and double blind trials Then peer review
26
What are monoclonal antibodies produced from
Lots of clones of a single white blood cell
27
How to produce monoclonal antibodies
Mouse injected with an antigen Lymphocytes which can produce specific antibodies taken Fused with a tumour cell to form a hybridoma which can produce the antibodies and divide rapidly Cloned Purified and stored
28
How are monoclonal antibodies used in pregnancy test
HCG binds to the antibodies HCG is only found in the urine of pregnant women It will 'stick' to the test strip
29
How can monoclonal antibodies be used to treat cancer
the antibodies, which are attached with an anti-cancer drug, can bind to the antigens on a tumour's surface it will kill just the tumour
30
How can monoclonal antibodies be used to test for substances
Bind to hormones and other chemicals in blood to measure their levels Test for pathogens Locate specific molecules on a cell/tissue Use a fluorescent dye bound to the MA first
31
Disadvantages of monoclonal antibodies
They can affect normal body cells when used to treat diseases Can cause more side effects than initially expected Expensive to develop
32
What does nitrate deficiency look like in plants
Stunted growth as nitrates are needed to make proteins
33
What does magnesium deficiency look like in plants
Yellow leaves as the plant is likely suffering from chlorosis as magnesium is needed for making chlorophyll
34
What are the common signs a plant has a disease
Stunted growth Abnormal growths Spots on leaves Malformed stems/leaves Discolouration
35
Examples of physical plant defences
Waxy cutices Layers of dead cells (bark) Cell walls They form a physical barrier against pathogens
36
Example of chemical plant defences
Antibacterial chemicals Poisons Secrete things to fight the pathogen
37
Example of mechanical plant defences
Thorns and hairs Drooping or curling Mimicking Putting predators off touching them