Infections Qs

Question 1

Which abx is preferred in asplenic pts?

Answer 1

PEN V

Question 2

PO treatment of fungal nail infection

Answer 2

Terbinafine

Question 3

BV treatment

Answer 3

Metro 400mg bd for 7 days

Question 4

Moderate to severe allergic rhinitis

Answer 4

1. Intranasal CS

• PO decongestants may provide short term relief but they can cause rebound congestion

Question 5

Doxycycline - with or without food

Answer 5

with food to prevent stomach ulcers

Question 6

Oxybutynin + ketoconazole =

Answer 6

increased AM SE

Question 7

Amoxicillin + warfarin

Answer 7

Amoxicillin reduces the metabolism of warfarin = increases effect leading to higher INR and risk of bleeding

Question 8

Amoxicillin + methotrexate =

Answer 8

increased risk of tox, amocillin reduces renal clearance

Question 9

Rubella virus

Answer 9

• Mild fever
• Lymphadenopathy
• Pink maculopapular rash – starts on face and spreads

Question 10

Can you give aciclovir cream in pregnancy?

Answer 10

YES

Question 11

Pseudomonas bronchiestasis treatment

Answer 11

Cipro 500mg bd for 7-14 days

Question 12

Treatment for cellulitis in penicillin allergy

Answer 12

Clindamycin

Question 13

Facial cellulitis

Answer 13

1. Flucloxacillin
2. Clari/erythro/doxy

Question 14

Doxy - headaches

Answer 14

If you get headache at start = normal
will subside

Question 15

Notifiable diseases

Answer 15

• rabies
• small pox
• covid
• malaria
• food poisoning

Question 16

Bronchitis treatment

Answer 16

1. doxy
2. preg: amo/ erythro

Question 17

Scarlett fever symptoms

Answer 17

• Sore throat
• High fever
• Strawberry tongue

Question 18

Gentamicin

Answer 18

• Broad spectrum acitivity
• Against aerobic Gram –
• P.aeruginosa – common in cystic fibrosis and bronchiestasis

Question 19

Trimethoprim SE

Answer 19

Fungal overgrowth

Question 20

metronidazole 2g PO single dose

Answer 20

BV

Question 21

Pen V main SE

Answer 21

colitis

Question 22

Macrolides main SE

Answer 22

o QT interval prolongation
o AA colitis
o Seizure
o Myasthenia gravis
o Pancreatitis

Question 23

Cephalasporin main SE

Answer 23

o Hypersenitivity
o Diarrhoea
o Vulvovaginal candidiasis
o Vomiting
o Thrombocytopenia

Question 24

Glycopeptide main SE

Answer 24

• infusion reaction
• red-man syndrome
• nephrotoxicity, ototoxicity

Question 25

Aminoglycosides

Answer 25

o Ototoxicity o Nephrotoxicity o Thrombocytopenia o Neuropathy o Renal damage

Question 26

Clarithromycin - pregancy

Answer 26

AVOID particulalry in 1st trimester

Question 27

Metronidazole - pregnancy

Answer 27

Avoid

Question 28

Chloramphenicol - pregnancy

Answer 28

Avoid Risk of neonatal 'grey-baby syndrome' if USED IN THIRD TRIMESTER;

Question 29

Tetracyclines - pregnancy

Answer 29

Avoid - effects on skeletal development - risk of discolouration of child's teeth in 2nd/3rd trimester!

Question 30

Aminoglycosides - pregnancy

Answer 30

- risk of auditory or vestibular nerve damage in the infant in 2ND/3RD TRIMESTER!

Question 31

Drugs to avoid in pregnancy | Carrying mothers cannot take antibiotics

Answer 31

Clari Metronidazole Chloramphenicol Tetracyclines Aminoglycosides

Question 32

Scarlett fever treatment

Answer 32

1. Phenoxymethylpenicillin 250mg qds for 10 days 2. Azithromycin 300mg once daily for 5 days

Question 33

Mastitis symptoms

Answer 33

- Burning pain in breast when breastfeeding - Swollen, red breasts - Fever

Question 34

When would you treat mastitis with ABx?

Answer 34

- Severe - systemically unwell - nipple fissures present - if symptoms do not improve after 12-24 hrs of effective milk removal - culture indicates infections

Question 35

Mastitis treatment

Answer 35

1. flucloxacillin - 10-14 days 2. If penicllin allergy: erythromycin - 10-14 days

Question 36

Green sputum

Answer 36

Bacterial

Question 37

Brown sputum

Answer 37

Chronic lung disease

Question 38

White sputum

Answer 38

Allergies/ viral

Question 39

Pink frothy sputum

Answer 39

HF

Question 40

Charcoal/grey sputum

Answer 40

Smokers

Question 41

hydroxychloroquine + azithromycin

Answer 41

increased risk of CV events

Question 42

Abx that causes liver failure

Answer 42

Co-amoxiclav

Question 43

Child with otitis media

Answer 43

Otigo

Question 45

diverticulitis treatment

Answer 45

co-amoxiclav 500/125mg tds for 5 days

Question 46

Infantile hypertrophic pyloris stenosis

Answer 46

risk is increased in the first 14 days after birth = erythromycin

Question 47

Pregnant woman with conjunctivitis

Answer 47

Fusidic acid

Question 48

Fexofenadine + erythromycin =

Answer 48

Increased levels of fexo Erythro = inhibitor

Question 49

Doxycycline + Gaviscon

Answer 49

Calcium carbonate = reduces absorption of doxycyline = decreased efficacy