Infections & Treatment

Question 1

Meningitis caused by meningococci

Answer 1

• Benzylpenicillin or cefotaxime - Chloramphenicol

Question 2

Meningitis caused by pneumococci

Answer 2

• Cefotaxime [add Dexamethasone]

- Benzylpen [ cephalosporin + vancomycin if pen allergic]

Question 3

Meningitis caused by Listeria

Answer 3

• Amoxicillin [or ampicillin] + gentamicin

- Co-trimoxazole [ if pen allergic]

Question 4

Meningitis caused by Haemophilus influenzae

Answer 4

• Cefotaxime [or cefriaxone]

Question 5

Conjunctivitis

Answer 5

• Chloramphenicol

Question 6

Otitis externa

Answer 6

• Flucloxacillin [counselling?]
• Clarithro/Azithro/Erythro -pen allergy
• Ciprofloxacin/ aminoglycoside [pseudomonas]

Question 7

Otitis media

Answer 7

• Amoxicillin
• Co-amoxiclav [worsening symptoms]
• Clarithro/Erythro [Pen allergy]

Question 8

Broad spec penicillins

Answer 8

Co amox, Amox, Phenoxy

Question 9

Cephalosporins

Answer 9

Cefalexin & cefradine

Question 10

Macrolides

Answer 10

Clar, erythro

Question 11

Endocarditis: Initial ‘blind’ therapy

Answer 11

Amoxicillin/ampicillin
- Add low dose Gentamicin
- Low dose Gentamicin + Vancomycin [ If penicillin
allergic/MRSA suspected or severe sepsis]

Question 12

Endocarditis: caused by staphylococci

Answer 12

• Flucloxacillin

- If pen allergy or MRSA [ Vancomycin + rifampicin]

Question 13

Endocarditis : caused by streptococci

Answer 13

Benzylpenicillin sodium. If pen allergy [ vancomycin + low

dose gentamicin]

Question 14

Blood Infection

Answer 14

• Piperacillin with Tazobactam/ Ticarcillin with clavulanic
  acid/ Cephalosporin broad spec [ e.g Cefuroxime]
• Add Vancomycin or teicoplanin [MRSA]
• Add Metronidazole to cephalosporin [anaerobic
  infection] [If other infection] use broad spec e.g
  Meropenem

Question 15

Campylobacter enteritis

Answer 15

Clar/azithro/Erythro -

ciprofloxacin

Question 16

Salmonella/shigellosis/Typhoid/Biliary infection

Answer 16

• Ciprofloxacin, Azithromycin , cefotaxime, gentamicin

Question 17

Clostridium difficile

Answer 17

Metronidazole - Vancomycin

Question 18

Lower urinary tract infections [non pregnant women]

Answer 18

Nitrofurantoin or Trimethoprim [1]

Fosfomycin/ Pivmecillinam [2]

Question 19

Lower urinary tract infections [pregnant women]

Answer 19

Nitrofurantoin [1]

Amoxicillin or cefalexin Catheter-pregnant : Cefalexin

Question 20

Bacterial Vaginosis

Answer 20

Metronidazole [oral/topical]

Question 21

Chlamydia

Answer 21

Azithromycin or Doxycycline[1],

Erythromycin

Question 22

Gonorrhoea

Answer 22

Azithromycin +[I.m

ceftriaxone/cefixime/ ciprofloxacin

Question 23

Syphillis

Answer 23

Benzylpenicillin , Erythro, Doxycycline

[asymptomatic]

Question 24

Epiglottitis

Answer 24

Cefotaxime or cefriaxone [1],Chloramphenicol [2] -

pen allergic

Question 25

COPD

Answer 25

Amoxicillin/clar/dox [1], co-amoxiclav, levofloxacin | or co-trimoxazole [2]

Question 26

Cough,acute

Answer 26

Doxycycline [1] or amox, Clar or erythro. | Pregnancy [ amox or erythro] [1]

Question 27

Pneumonia [community]

Answer 27

Amox [1] , [erythro/dox,clar pen allergic]

Question 28

Impetigo Topical

Answer 28

Hydrogen peroxide 1% cream] [1] , | fusidic acid [2],

Question 29

Impetigo Oral

Answer 29

Flucloxacillin [1], [clarithro, erythro for pen | allergy]

Question 30

Cellulitis

Answer 30

Flucloxacillin [1] [clari, ery, dox pen allergy], co- | amoxiclav, clindamycin[2]

Question 31

Leg ulcer

Answer 31

Fluclox[1] [clar, ery, dox pen allergy], co- | trimoxazole [pen allergy] 2

Question 32

Animal & human bite

Answer 32

Co-amoxiclav [1], [pen allergic, Doxycycline | + Metronidazole]

Question 33

Mastitis during breastfeeding

Answer 33

Flucloxacillin [pen allergic, erythromycin] 2

Question 34

Osteomyelitis

Answer 34

Flucloxacillin | If penicillin allergic : Clindamycin [2]

Question 35

Diabetic | foot

Answer 35

Flucloxacillin [1] [Mild infection] If pen allergy or fluclox unsuitable [ clarithro/ Doxy/erythro [preg]] [2]