Infectious Disease Flashcards

(34 cards)

1
Q

Antibiotic choices for pneumonia

A

Azithro if atypical
Amox = outpatients
Amp = inpatients
CTX = resp failure, septic shock
Add vanco if decompensating

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2
Q

Pneumonia treatment duration

A

Mild = 5 days
Most patients = 7-10 days
Complicated = 2-4 weeks

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3
Q

Parinaud oculoglandular syndrome

A

Unilateral conjunctivitis and preauricular lymphadenopathy
From direct eye inoculation with Bartonella

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4
Q

Cat scratch disease

A

Most common cause of chronic regional lymphadenitis
Usually axillary or cervical
Primary skin lesion precedes lymphadenopathy
Can also get non specific and systemic symptoms
Dx with serology or PCR
Usually self resolves in 2-4 months, but 5 days of azithro can speed recovery
Do NOT I+D, can cause sinus tract

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5
Q

Mycobacterium avium lymphadenitis

A

Subacute, painless, rubbery-firm, blueish tinged
Cervicofacial nodes
Can become suppurative
Excision is diagnostic and therapeutic

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6
Q

Flu vaccine recommendations

A

6+ months, annually
First year and < 9 years: 2 doses, 4 weeks apart
IN can only be used for 2-17 year olds
Contraindications: GBS, NOT egg allergy
IN cannot be used < 2 years, immunocompromised, severe asthma, receiving ASA, pregnant

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7
Q

Measles infectious period

A

3 days before to 4-6 days after RASH onset

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8
Q

Infection risk with powdered formula

A

Enterobacter sakazakii

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9
Q

How long to wait post IVIG to give
1. Live
2. Inactivated
vaccines

A
  1. 11 months
  2. No need to wait
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10
Q

PANDAS

A

Pediatric autoimmune neuropsychiatric disorders associated with S pyogenes
Hypothesized relationship, thought to be from cross reactivity of autoimmune antibodies
IVIG is proposed management

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11
Q

What abx to use for GBS + moms if they are allergic to penicillin

A

Cefazolin if low risk for anaphylaxis
Clinda if sensitive to clinda and erythro
Vanco if unknown susceptibilities or resistant to clinda
Clinda and vanco should be treated as inadequate prophylaxis

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12
Q

Abx choice for empiric abx in
1. 0-7 days
2. 8-28 days
3. 29-60 days
4. 61-90 days

A
  1. amp and gent/tobra, can use cefotax if concerns for meningitis
  2. same as above
  3. ceftriaxone + vanco if concerns for meningitis
  4. same as above
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13
Q

UTI in infants 1-3 mo

A

If low risk, can treat with PO cefixime

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14
Q

Gianotti-Crosti syndrome

A

Papular acrodermatitis of childhood
Due to EBV
Mildly itchy, papular, symmetric on face, buttocks, extensor surfaces

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15
Q

How long to avoid sports with EBV

A

21 days

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16
Q

Simple abscess management
1. < 1 mo
2. 1-3 mo
3. > 3 mo and well
4. > 3 mo with fever/cellulitis
5. All other scenarios

A

<1 mos = IV Abx
1 to 3 mos = PO Septra
>3 mos and well = I&D alone
>3 mos with fever/cellulitis = PO Septra + Keflex
Other scenarios usually need IV abx

17
Q

Ramsay-Hunt syndrome

A

Shingles (VZV) involving portion of facial nerve near the ear
Vesicular rash on ear and facial weakness/paralysis
Triad: unilateral facial palsy, otalgia, vesicles in ear
Treat with antivirals and high dose steroids

18
Q

Failed AOM with amox, next line treatment

A

Amox clav
Could be due to H flu or Moraxella

19
Q

Limits to when vaccines can be given pre biologics

A

4 weeks before for live vaccines
2 weeks before for inactivated

20
Q

Definition of C diff infections
1. Mild
2. Moderate
3. Severe
4. Severe, complicated

A
  1. < 4 stools per day
  2. 4 + stools a day
  3. Systemic toxicity
  4. Systemic toxicity and severe colitis (shock, peritonitis, ileus, megacolon)
21
Q

Management of C diff infections
1. Mild
2. Moderate
3. Severe
4. Severe, complicated
5. First recurrence
6. Second recurrence

A

Discontinue antibiotics for all
1. Follow and reassess
2. Flagyl 10-14 d
3. Vanco 10-14 d
4. Vanco and Flagyl 10-14 d
5. Repeat regimen that worked > vanco x 10 d
6. Vanco tapered or pulsed

22
Q

How to diagnose
1. Early
2. Late
Lyme disease

A
  1. Clinical (serology not helpful in first 4 weeks)
  2. ELISA then Western Blot
23
Q

Management of
1. Early cutaneous
2. Late extracutaneous
Lyme disease

A
  1. Doxycycline x 10 days (or amox, cefuroxime, azithro)
  2. Doxycycline (CTX if persistent arthritis, meningitis, heart block)
24
Q

Jarisch-Herxheimer reaction

A

Fever, headache, myalgia with initiation of antibiotics
Keep treating, NSAIDs for comfort

25
Prophylaxis for Lyme
Single dose doxycycline after a tick bite Start within 72 hours Only use if tick was attached for > 36 hours
26
How to treat isolated SNHL from CMV
6 weeks of valganciclovir
27
2 vaccines most important for preschoolers
Hib Pneumococcal
28
Testing infants born to HCV positive mothers
HCV RNA at 2-6 months If negative repeat serology at 18-24 months If someone has done serology and baby is negative at 6 or more months, no need to retest
29
Treatment of necrotizing fasciitis
Secondary to strep infection Penicillin + clinda If risk factors for it being another bacteria, treat with pip-tazo or a carbapenem + clindamycin +/- vanco
30
What tetanus prophylaxis is needed for clean, minor wounds
Never need immunoglobulin If immunization history is unknown, < 3 doses in series, or > 10 years since booster = give tetanus containing vaccine (3rd dose of vaccine is at 6 months)
31
What tetanus prophylaxis is needed for NOT clean/minor wounds
Immunoglobulin needed if unknown immunization status or < 3 vaccines Vaccine should be given to ALL except those who have 3+ vaccines and are < 5 years from booster
32
When is parvovirus no longer infectious
Once rash appears
33
Varicella post exposure prophylaxis for susceptible persons if 1. Healthy 2. Pregnant 3. Immunocompromised
1. Give vaccine 2/3. Check VZV IgG, if negative give immunoglobulin
34
Gradenigo syndrome
Otitis media/mastoiditis/otorrhea + facial pain in trigeminal nerve area + abducens palsy