Infectious Disease Flashcards

1
Q

Which viruses are enveloped and obtain the envelope from the nuclear membrane?

A

Herpesviruses (CMV, EBV, HSV, etc)

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2
Q

Described the clinical manifestation of Typhoid Fever.

A

Week 1 - Rising Fever, Bacteremia, Bradycard
Week 2 - Abd Pain and Rose spots on Trunk/Abd
Week 3- Hepatospelomegaly, Bleeding/Perforation

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3
Q

IgA Protease in Encaps bacteria (ie N men, N gonn, Strep Pneumo) helps bacteria do what?

A

Facilitates mucosal adherence

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4
Q

HPV infects what type of cells? Where can these be found?

A

Stratified Squamos Epithelium - Anal, Vaginal, Cervix, TRUE Vocal cords

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5
Q

Babeiosis

A

Babesia Microti - Ixodes Scapularis Tick - NE USA

Flulike Symptoms w/ anemia, Thrombocytopenia, ^LFTs

Blood smear shows Intraerythrocytic Rings/Inclusions (Maltese Crosses)

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6
Q

What would you see on Microscopy of Cryptococcus Neoformans?

A

BUDDING YEAST - Encapsulated cells - Polysaccharide Capsule (Latex Agglutinaiton) - Culture on Saborauds Agar

Lung infection and Meningioencephalitis

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7
Q

Eccinococcus Granuloso…?

A

Hyatid Cyst. Southwest US. Exposure to sheep and dogs.

Often affects liver. Get cysts in Liver. Eggshell Calcificaiton. Surgical Disruption can cause ANAPHYLAXIS.

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8
Q

Describe Pseudomonas.

A

Gram -, NON-lactose fermenting, oxidase +, creates GREEN pigment.

UTI, Lung, Hot tub foliculitis

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9
Q

Marker of Osteoblast activity..? Osteoclast…?

A

Osteoblast - Serum (bone specific) Alk Phos

Osteoclast - Serum Acid Phosphatase, Urine Hydroxyproline and Deoxypyridolinine

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10
Q

HIV pt with large mass in small intestine, Ki 67 fraction >99%….?

A

EBV associated Burkitt Lymphoma

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11
Q

Toxicity of Acyclovir…? How to prevent?

A

Nephrotoxicity….IV Hydration to prevent

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12
Q

What is the toxin in C.Perfringes?

A

Lecithinase aka Alpha Toxin aka Phopholipase C.

Splits phospholipid molecules causing lysis, necorsis, edema

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