Infectious Disease

Question 1

What are penicillins good at treating?

Answer 1

strep/staph, syphilis

Question 2

What is vanco good at covering?

Answer 2

gram-pos and c. diff (PO)

Question 3

What are macrolides good at covering?

Answer 3

atypicals and ppl with PCN allergy

Question 4

What is clindamycin used for?

Answer 4

additional anearobic coverage

Question 5

What are common SE of flouroquinolones?

Answer 5

prolonged QT, cartilage damage, tendon rupture

Question 6

What are common SE of aminoglcosides?

Answer 6

ototoxicity (irreversible), nephrotoxicity (reversible)

Question 7

What are aminoglucycosides good at covering?

Answer 7

gram-neg

Question 8

What is metronidazole good at covering?

Answer 8

anaerobes and C. diff

Question 9

Patient who is a cattle farmer presents with black eschar rash, pneumonia and N/V/D

Answer 9

anthrax

Question 10

What is anthrax?

Answer 10

gram-pos spore-forming rod

Question 11

What is tx of anthrax?

Answer 11

cipro or doxy

Question 12

Patient returns from mexico and has bloody diarrhea, fever, maliase, abd pain

Answer 12

salmonella

Question 13

How do you tx salmonella?

Answer 13

cipro x2 weeks

Question 14

What is presentation of shigella?

Answer 14

diarrhea, cramps

Question 15

How do you treat shigella?

Answer 15

only if severe, bactrim or flouroquinolone

Question 16

Patient presents with rice water stools, and no fecal odor

Answer 16

cholera

Question 17

How do you tx cholera?

Answer 17

macrolide

Question 18

How do you dx rocky mountain spotted?

Answer 18

ELISA then western blot

Question 19

How do you treat rocky mountain spotted?

Answer 19

doxycycline

Question 20

Where do you see tularemia?

Answer 20

Arkansas, Oklahoma

Question 21

How do you treat tularemia?

Answer 21

gentamicin or tetracycline

Question 22

How do you dx malaria?

Answer 22

blood smear

Question 23

What is tx of malaria?

Answer 23

chloroquine

Question 24

Patient has multiple ring-enhacing lesion son CT scan

Answer 24

toxoplasmosis

Question 25

What is tx of toxoplasmosis?

Answer 25

pytimethamine and sulfadiazine

Question 26

Patient presents with bloody diarrhea and hepatic abscess

Answer 26

amebiasis

Question 27

What is tx of amebiasis?

Answer 27

metronidazole

Question 28

Patient presents after camping with diarrhea and greasy foul smelling stools w/o blood

Answer 28

giardia

Question 29

What is tx for giardia?

Answer 29

metronidazole

Question 30

What is associated with schistosomiasis?

Answer 30

snails

Question 31

What is assocaited with infected pork?

Answer 31

trichinosis

Question 32

What do you treat worms with?

Answer 32

albendaole and mebendazole

Question 33

When is someone considered to have AIDS?

Answer 33

CD4 under 200 or AIDS-defining condition

Question 34

CD4 under 200 diseases

Answer 34

Kaposi sarcoma, TB, oral thrush, PCP, lymphoma, oral hairy leukoplakia

Question 35

How do you treat PCP pna?

Answer 35

bactrim

Question 36

What causes kaposi sarcoma?

Answer 36

human herpes virus 8 (HHV8)

Question 37

CD4 under 100 diseases

Answer 37

toxoplasmosis, cryptococcosis, disseminated candida

Question 38

CD4 under 50

Answer 38

CMV, MAC

Question 39

How do you treat CMV?

Answer 39

gangciclovir

Question 40

How do you treat MAC?

Answer 40

macrolide

Question 41

philadelphia chormosome

Answer 41

CML

Question 42

How do you treat CML?

Answer 42

imatinib, chemo, BM transplant

Question 43

Aure rods

Answer 43

AML

Question 44

what age does AML usually occur?

Answer 44

over 60yo

Question 45

Which leukemia is tolerated well for years?

Answer 45

CLL

Question 46

How do you treat CLL?

Answer 46

rituximab, prednisone, fludarabine

Question 47

What age does ALL affect?

Answer 47

kids usually

Question 48

What is multiple myeloma?

Answer 48

malignant plasma cells

Question 49

What sxs are associated with multiple myeloma?

Answer 49

hyperCa, fx, renal failure, anemia

Question 50

When do you see bence jones proteins?

Answer 50

multiple myeloma

Question 51

how do you treat multiple myeloma?

Answer 51

clacitonin, biphosphonates, alkylating agents, thalodomide, prednosone, BM transplant

Question 52

What is caused by antibodies against platelets causing thrombocytopenia?

Answer 52

ITP

Question 53

What is tx for ITP?

Answer 53

steroids acutely, IVIG, splenectomy

Question 54

Patient presents with renal failure, hemolytic anemia, thrombocytopenia, and neuro changes and fever

Answer 54

TTP/HUS

Question 55

What are risk factors for TTP/HUS?

Answer 55

E. coli 0157:H7

Question 56

What is treatment for TTP/HUS?

Answer 56

plasmaphoresis, FFP

Question 57

What shouldn't you do in TTP/HUS?

Answer 57

platelet transfusions

Question 58

When does HIT occur?

Answer 58

5-10 days after exposure to heparin

Question 59

What is treatment of HIT?

Answer 59

anticoag (argatroban, dabigatran)

Question 60

basophilic stippling

Answer 60

sideroblastic anemia

Question 61

What causes sideroblastic anemia?

Answer 61

lead poisoning